Epigenetic modification refers to heritable changes in gene function that cannot be
explained by alterations in the DNA sequence. The current literature clearly demonstrates …

Sex differences in exercise physiology, such as substrate metabolism and skeletal muscle
fatigability, stem from inherent biological factors, including endogenous hormones and …

How mechanical stress affects physical performance via tendons is not fully understood.
Piezo1 is a mechanosensitive ion channel, and E756del PIEZO1 was recently found as a …

An individual's dietary and supplement strategies can influence markedly their physical
performance. Personalized nutrition in athletic populations aims to optimize health, body …

Human athletic performance is a complex phenotype influenced by environmental and
genetic factors, with most exercise-related traits being polygenic in nature. The aim of this …

Sports genomics is the scientific discipline that focuses on the organization and function of
the genome in elite athletes, and aims to develop molecular methods for talent identification …

Background Cardiorespiratory fitness (VO 2max) is an excellent predictor of chronic disease
morbidity and mortality risk. Guidelines recommend individuals undertake exercise training …

Phenotypes of athletic performance and exercise capacity are complex traits influenced by
both genetic and environmental factors. This update on the panel of genetic markers (DNA …

For centuries, regular exercise has been acknowledged as a potent stimulus to promote,
maintain, and restore healthy functioning of nearly every physiological system of the human …

Human physiology is likely to have been selected for endurance physical activity. However,
modern humans have become largely sedentary, with physical activity becoming a leisure …