Glycemic homeostasis refers to glucose balance or control within circulation in living
organisms. It is normally and largely compromised in diabetes. The compromise when …

Diabetes mellitus is a chronic metabolic disorder with a high prevalence worldwide. Animal
models of diabetes represent an important tool in diabetes investigation that helps us to …

Alloxan and streptozotocin are toxic glucose analogues that preferentially accumulate in
pancreatic beta cells via the GLUT2 glucose transporter. In the presence of intracellular …

Diabetes mellitus is a metabolic disorder constituting a major health concern today whose
prevalence has continuously increased worldwide over the past few decades. Moreover, it …

Traffic is a major source of particulate matter (PM), and ultrafine particulates and traffic
intensity probably contribute significantly to PM-related health effects. As a strong …

This study was aimed to evaluate the hypoglycaemic and hypolipidemic effects of different
doses of pumpkin (Cucurbita pepo L.) powder in male diabetic rats. A total of 35 rats were …

11beta-Hydroxysteroid dehydrogenases (11beta-HSDs) interconvert active corticosterone
and inert 11-dehydrocorticosterone. In tissue homogenates, 11beta-HSD type 1 (11beta …

Objective To isolate and characterize antidiabetic component (bioactivity-guided
fractionation) from hydro alcoholic extract of Ocimum sanctum (O. sanctum) aerial part …

Spirulina platensis (Spi) is a microalga presenting high contents of proteins, γ-linolenic acid,
vitamins and minerals, and showing many biological activities. It is a promising drug for the …

Background Increased production of reactive oxygen species (ROS) and oxidative stress are
known to play a key role in the pathogenesis of type 2 diabetes (T2D); however, the …