NK cells are never alone: crosstalk and communication in tumour microenvironments

Y Zhou, L Cheng, L Liu, X Li - Molecular Cancer, 2023 - Springer
Immune escape is a hallmark of cancer. The dynamic and heterogeneous tumour
microenvironment (TME) causes insufficient infiltration and poor efficacy of natural killer (NK) …

Regulation of ligands for the NKG2D activating receptor

DH Raulet, S Gasser, BG Gowen… - Annual review of …, 2013 - annualreviews.org
NKG2D is an activating receptor expressed by all NK cells and subsets of T cells. It serves
as a major recognition receptor for detection and elimination of transformed and infected …

[HTML][HTML] Decidual NK cells transfer granulysin to selectively kill bacteria in trophoblasts

ÂC Crespo, S Mulik, F Dotiwala, JA Ansara, SS Santara… - Cell, 2020 - cell.com
Maternal decidual NK (dNK) cells promote placentation, but how they protect against
placental infection while maintaining fetal tolerance is unclear. Here we show that human …

Trophic effects of mesenchymal stem cells in tissue regeneration

Y Fu, L Karbaat, L Wu, J Leijten, SK Both… - … Engineering Part B …, 2017 - liebertpub.com
Mesenchymal stem cells (MSCs) are considered to hold great therapeutic value for cell-
based therapy and for tissue regeneration in particular. Recent evidence indicates that the …

Intercellular communication: diverse structures for exchange of genetic information

M Mittelbrunn, F Sánchez-Madrid - Nature reviews Molecular cell …, 2012 - nature.com
An emerging concept is that cellular communication in mammals can be mediated by the
exchange of genetic information, mainly in the form of microRNAs. This can occur when …

Recognition of tumors by the innate immune system and natural killer cells

A Marcus, BG Gowen, TW Thompson, A Iannello… - Advances in …, 2014 - Elsevier
In recent years, roles of the immune system in immune surveillance of cancer have been
explored using a variety of approaches. The roles of the adaptive immune system have been …

Tunneling nanotube (TNT)-mediated neuron-to neuron transfer of pathological Tau protein assemblies

M Tardivel, S Bégard, L Bousset, S Dujardin… - Acta neuropathologica …, 2016 - Springer
A given cell makes exchanges with its neighbors through a variety of means ranging from
diffusible factors to vesicles. Cells use also tunneling nanotubes (TNTs), filamentous-actin …

Mesenchymal stem cells rescue injured endothelial cells in an in vitro ischemia–reperfusion model via tunneling nanotube like structure-mediated mitochondrial …

K Liu, K Ji, L Guo, W Wu, H Lu, P Shan, C Yan - Microvascular research, 2014 - Elsevier
Mesenchymal stem cells can be used as a novel treatment of ischemic vascular disease;
however, their therapeutic effect and mechanism of action require further evaluation …

Peering into tunneling nanotubes—The path forward

D Cordero Cervantes, C Zurzolo - The EMBO journal, 2021 - embopress.org
Abstract The identification of Tunneling Nanotubes (TNTs) and TNT‐like structures signified
a critical turning point in the field of cell‐cell communication. With hypothesized roles in …

Wiring through tunneling nanotubes–from electrical signals to organelle transfer

S Abounit, C Zurzolo - Journal of cell science, 2012 - journals.biologists.com
Tunneling nanotubes (TNTs) represent a subset of F-actin-based transient tubular
connections that allow direct communication between distant cells. Recent studies have …