The 18 kDa translocator protein (TSPO), previously known as the peripheral
benzodiazepine receptor, is predominately localized to the outer mitochondrial membrane in …

Traumatic brain injury (TBI) remains a significant source of death and permanent disability,
contributing to nearly one-third of all injury related deaths in the United States and exacting …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most
common cause of dementia. Beta-amyloid (Aβ) deposition and neurofibrillary tangles (NFTs) …

The 18 kDa translocator protein (TSPO), previously known as the peripheral
benzodiazepine receptor, is expressed in the injured brain. It has become known as an …

Second-generation radioligands for translocator protein (TSPO), an inflammation marker,
are confounded by the codominant rs6971 polymorphism that affects binding affinity. The …

Adaptation of the nervous system to different chemical and physiologic conditions is
important for the homeostasis of brain processes and for learning and remembering …

The 18-kDa TSPO (translocator protein) localizes on the outer mitochondrial membrane
(OMM) and participates in cholesterol transport. Here, we report that TSPO inhibits …

Inflammation is a highly dynamic and complex adaptive process to preserve and restore
tissue homeostasis. Originally viewed as an immune-privileged organ, the central nervous …

Neuroinflammation is heavily associated with various neurological diseases including
Alzheimer's disease, Parkinson's disease, multiple sclerosis, and stroke. It is strongly …

Translocator protein 18 kDa (TSPO) is a transmembrane protein in the mitochondrial
membrane, which has been identified as a peripheral benzodiazepine receptor. TSPO is …