Multifaceted highly targeted sequential multidrug treatment of early ambulatory high-risk SARS-CoV-2 infection (COVID-19)

PA McCullough, PE Alexander… - Reviews in …, 2020 - scholarlycommons.henryford.com
The SARS-CoV-2 virus spreading across the world has led to surges of COVID-19 illness,
hospitalizations, and death. The complex and multifaceted pathophysiology of life …

[HTML][HTML] Different anticoagulant regimens, mortality, and bleeding in hospitalized patients with COVID-19: a systematic review and an updated meta-analysis

R Parisi, S Costanzo, A Di Castelnuovo… - … in thrombosis and …, 2021 - thieme-connect.com
We conducted a systematic review and a meta-analysis to assess the association of
anticoagulants and their dosage with in-hospital all-cause mortality in COVID-19 patients …

[HTML][HTML] Early initiation of prophylactic anticoagulation for prevention of coronavirus disease 2019 mortality in patients admitted to hospital in the United States: cohort …

CT Rentsch, JA Beckman, L Tomlinson, WF Gellad… - Bmj, 2021 - bmj.com
Objective To evaluate whether early initiation of prophylactic anticoagulation compared with
no anticoagulation was associated with decreased risk of death among patients admitted to …

Diagnostic value of D-dimer in COVID-19: a meta-analysis and meta-regression

H Zhan, H Chen, C Liu, L Cheng… - Clinical and Applied …, 2021 - journals.sagepub.com
The prognostic role of hypercoagulability in COVID-19 patients is ambiguous. D-dimer, may
be regarded as a global marker of hemostasis activation in COVID-19. Our study was to …

[HTML][HTML] Heparin in COVID-19 patients is associated with reduced in-hospital mortality: the multicenter Italian CORIST study

A Di Castelnuovo, S Costanzo… - Thrombosis and …, 2021 - thieme-connect.com
Introduction A hypercoagulable condition was described in patients with coronavirus
disease 2019 (COVID-19) and proposed as a possible pathogenic mechanism contributing …

[HTML][HTML] Sulodexide in the treatment of patients with early stages of COVID-19: a randomized controlled trial

AJ Gonzalez-Ochoa, JD Raffetto… - Thrombosis and …, 2021 - thieme-connect.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may induce several
vascular endothelial-dependent systemic complications, and sulodexide has pleiotropic …

[HTML][HTML] Venous thromboembolism in patients discharged after COVID-19 hospitalization

MM Engelen, C Vandenbriele… - … in thrombosis and …, 2021 - thieme-connect.com
Background Venous thromboembolism (VTE) is a frequent complication of COVID-19, so
that the importance of adequate in-hospital thromboprophylaxis in patients hospitalized with …

[HTML][HTML] A phase 2 single center open label randomised control trial for convalescent plasma therapy in patients with severe COVID-19

Y Ray, SR Paul, P Bandopadhyay, R D'Rozario… - Nature …, 2022 - nature.com
A single center open label phase 2 randomised control trial (Clinical Trial Registry of India
No. CTRI/2020/05/025209) was done to assess clinical and immunological benefits of …

Good practice statements for antithrombotic therapy in the management of COVID‐19: Guidance from the SSC of the ISTH

AC Spyropoulos, JM Connors… - … of Thrombosis and …, 2022 - Wiley Online Library
Despite the emergence of high quality randomized trial data with the use of antithrombotic
agents to reduce the risk of thromboembolism, end‐organ failure, and possibly mortality in …

[HTML][HTML] Using automated machine learning to predict the mortality of patients with COVID-19: prediction model development study

K Ikemura, E Bellin, Y Yagi, H Billett, M Saada… - Journal of medical …, 2021 - jmir.org
Background During a pandemic, it is important for clinicians to stratify patients and decide
who receives limited medical resources. Machine learning models have been proposed to …