Zwitterionic biomaterials

Q Li, C Wen, J Yang, X Zhou, Y Zhu, J Zheng… - Chemical …, 2022 - ACS Publications
The term “zwitterionic polymers” refers to polymers that bear a pair of oppositely charged
groups in their repeating units. When these oppositely charged groups are equally …

Anti-PEG antibodies in the clinic: Current issues and beyond PEGylation

P Zhang, F Sun, S Liu, S Jiang - Journal of Controlled Release, 2016 - Elsevier
The technique of attaching the polymer polyethylene glycol (PEG), or PEGylation, has
brought more than ten protein drugs into market. The surface conjugation of PEG on proteins …

Neurotoxicity in acute and repeated organophosphate exposure

SX Naughton, AV Terry Jr - Toxicology, 2018 - Elsevier
The term organophosphate (OP) refers to a diverse group of chemicals that are found in
hundreds of products worldwide. As pesticides, their most common use, OPs are clearly …

Applications of zwitterionic polymers

L Zheng, HS Sundaram, Z Wei, C Li, Z Yuan - Reactive and Functional …, 2017 - Elsevier
Zwitterionic polymers are characterized with equal anion and cation groups on the
molecular chains, which make them highly hydrophilic and antifouling. They can resist …

Surface-adaptive zwitterionic nanoparticles for prolonged blood circulation time and enhanced cellular uptake in tumor cells

H Ou, T Cheng, Y Zhang, J Liu, Y Ding, J Zhen… - Acta biomaterialia, 2018 - Elsevier
Recently, zwitterionic materials have been developed as alternatives to PEG for prolonging
the circulation time of nanoparticles without triggering immune responses. However …

Cholinesterases and the fine line between poison and remedy

CN Pope, S Brimijoin - Biochemical pharmacology, 2018 - Elsevier
Abstract Acetylcholinesterase (AChE, EC 3.1. 1.7) and butyrylcholinesterase (BChE, EC 3.1.
1.8) are related enzymes found across the animal kingdom. The critical role of …

Cholinesterase reactivators and bioscavengers for pre‐and post‐exposure treatments of organophosphorus poisoning

P Masson, F Nachon - Journal of neurochemistry, 2017 - Wiley Online Library
Organophosphorus agents (OP s) irreversibly inhibit acetylcholinesterase (AC hE) causing a
major cholinergic syndrome. The medical counter‐measures of OP poisoning have not …

[图书][B] Human drug metabolism

MD Coleman - 2020 - books.google.com
Provides a timely update to a key textbook on human drug metabolism The third edition of
this comprehensive book covers basic concepts of teaching drug metabolism, starting from …

Responsive crosslinked polymer nanogels for imaging and therapeutics delivery

AE Ekkelenkamp, MR Elzes, JFJ Engbersen… - Journal of Materials …, 2018 - pubs.rsc.org
Water-soluble, nano-sized crosslinked polymer networks, or nanogels, are delivery vehicles,
which have highly interesting properties for therapeutic delivery and imaging. Nanogels may …

Achieving ultralow fouling under ambient conditions via surface-initiated ARGET ATRP of carboxybetaine

D Hong, HC Hung, K Wu, X Lin, F Sun… - … applied materials & …, 2017 - ACS Publications
We achieved ultralow fouling on target surfaces by controlled polymerization of
carboxybetaine under ambient conditions. The polymerization process for grafting polymer …