Effects of alpha lipoic acid on metabolic syndrome: a comprehensive review

N Najafi, S Mehri… - Phytotherapy …, 2022 - Wiley Online Library
Metabolic syndrome (MetS) is a multifactorial disease with medical conditions such as
hypertension, diabetes, obesity, dyslipidemia, and insulin resistance. Alpha‐lipoic acid (α …

[HTML][HTML] Plasma membranes as heat stress sensors: from lipid-controlled molecular switches to therapeutic applications

Z Török, T Crul, B Maresca, GJ Schütz, F Viana… - … et Biophysica Acta (BBA …, 2014 - Elsevier
The classic heat shock (stress) response (HSR) was originally attributed to protein
denaturation. However, heat shock protein (Hsp) induction occurs in many circumstances …

Vascular dysfunction and chronic obstructive pulmonary disease: the role of redox balance

SJ Ives, RA Harris, MAH Witman, AS Fjeldstad… - …, 2014 - Am Heart Assoc
Chronic obstructive pulmonary disease (COPD) is characterized by low pulmonary function,
inflammation, free radical production, vascular dysfunction, and subsequently a greater …

[HTML][HTML] Antioxidant properties of alpha-lipoic (thioctic) acid treatment on renal and heart parenchyma in a rat model of hypertension

I Martinelli, D Tomassoni, P Roy, L Di Cesare Mannelli… - Antioxidants, 2021 - mdpi.com
Renal and cardiac impairments are frequent events in the presence of hypertension. Organ
damage is mainly linked to oxidative stress due to high blood pressure and may be reduced …

Alpha lipoic acid supplementation attenuates reactive oxygen species in hypothalamic paraventricular nucleus and sympathoexcitation in high salt-induced …

Q Su, JJ Liu, W Cui, XL Shi, J Guo, HB Li, CJ Huo… - Toxicology letters, 2016 - Elsevier
Aims High salt-induced oxidative stress plays an important role in the development of
hypertension. Alpha lipoic acid (ALA) is extensively recognized as having a powerful …

Coconut oil supplementation and physical exercise improves baroreflex sensitivity and oxidative stress in hypertensive rats

NFB Alves, SKP Porpino, MMO Monteiro… - Applied Physiology …, 2015 - cdnsciencepub.com
The hypothesis that oral supplementation with virgin coconut oil (Cocos nucifera L.) and
exercise training would improve impaired baroreflex sensitivity (BRS) and reduce oxidative …

Dietary nitrate reduces blood pressure in rats with angiotensin II–induced hypertension via mechanisms that involve reduction of sympathetic hyperactivity

DD Guimarães, JC Cruz, A Carvalho-Galvão… - …, 2019 - Am Heart Assoc
Several experimental and clinical studies have shown that dietary nitrate supplementation
can increase nitric oxide bioavailability. In the oral cavity, commensal bacteria reduce nitrate …

[HTML][HTML] Involvement of shedding induced by ADAM17 on the nitric oxide pathway in hypertension

MC da Silva, VM Dos Santos, MVB da Silva… - Frontiers in Molecular …, 2022 - frontiersin.org
A Disintegrin and Metalloprotease 17 (ADAM17), also called tumor necrosis factor-ɑ (TNF-
ɑ) convertase (TACE), is a well-known protease involved in the sheddase of growth factors …

[HTML][HTML] Angiotensin-II-derived reactive oxygen species on baroreflex sensitivity during hypertension: new perspectives

TM de Queiroz, MMO Monteiro, VA Braga - Frontiers in physiology, 2013 - frontiersin.org
Hypertension is a multifactorial disorder, which has been associated with the reduction in
baroreflex sensitivity (BRS) and autonomic dysfunction. Several studies have revealed that …

[HTML][HTML] R-is superior to S-form of α-lipoic acid in anti-inflammatory and antioxidant effects in laying hens

Q Liu, W Li, S Huang, L Zhao, J Zhang, C Ji, Q Ma - Antioxidants, 2022 - mdpi.com
The development of single enantiomers with high efficiency and low toxic activity has
become a hot spot for the development and application of drugs and active additives. The …