Objective To assess the effectiveness and cost-effectiveness of primary care (PC) and sleep
unit (SU) models for the management of subjects with suspected obstructive sleep apnoea …

Purpose As patient-reported outcome measures (PROMs) are increasingly integrated into
clinical practice, there is a need to translate collected data into valuable information to guide …

Background Total hip and knee arthroplasties (THA/TKA) are clinically effective but high cost
procedures. The aim of this study is to perform a cost-effectiveness analysis of THA and TKA …

Abstract Objective The Western Ontario and McMaster Universities Osteoarthritis (WOMAC)
pain scale quantifies knee pain severity with activities of daily living, but the potential impact …

ABSTRACT AIM: A key Government health target has been to increase access to elective
surgery. Despite this, there is a growing concern about unmet demand and increasing …

Objectives Intra‐articular injection of hyaluronic acid (HA) is a common, yet controversial
therapeutic option in treating knee osteoarthritis (OA). The purpose of the present study was …

Background: Heart failure (HF) is a costly health condition and a major public health
problem. It is estimated that 2%-3% of the population in developed countries has HF, and …

Minimal clinically important difference (MCID) estimates have been endorsed for substantive
clinical practice and research-based decisions1. In clinical practice, MCIDs are utilized to …

Background. There is growing evidence that quality of life (QoL) has a strong association
with mortality. However, incorporation of QoL is uncommon in standard survival modeling …

Governments and health insurers often make funding decisions based on health gains from
randomised controlled trials. These decisions are inherently uncertain because health gains …