[HTML][HTML] Anticancer drugs in the aquatic ecosystem: Environmental occurrence, ecotoxicological effect and risk assessment

D Li, H Chen, H Liu, D Schlenk, J Mu, S Lacorte… - Environment …, 2021 - Elsevier
Anticancer drugs are a group of therapeutic agents used to enhance cell death in targeted
cell types of neoplasia. Because of frequent use and eventual discharge, they have been …

[HTML][HTML] Cytostatic pharmaceuticals as water contaminants

M Jureczko, J Kalka - European journal of pharmacology, 2020 - Elsevier
Due to the growing problem of cancer diseases, cytostatic drugs have become a great
environmental threat. Their main sources are hospital effluents, household discharge and …

Chemical and toxicological characterisation of anticancer drugs in hospital and municipal wastewaters from Slovenia and Spain

M Isidori, M Lavorgna, C Russo, M Kundi… - Environmental …, 2016 - Elsevier
Anticancer drugs are continuously released into hospital and urban wastewaters, where
they, most commonly, undergo conventional treatment in wastewater treatment plants …

Emerging pollutants in Nigeria: A systematic review

C Egbuna, CN Amadi, KC Patrick-Iwuanyanwu… - Environmental …, 2021 - Elsevier
Emerging pollutants represent a group of synthetic or naturally occurring compounds that
are not normally monitored within the environment but can enter into the environment and …

Presence of the pharmaceutical drug carbamazepine in coastal systems: effects on bivalves

 Almeida, V Calisto, VI Esteves, RJ Schneider… - Aquatic toxicology, 2014 - Elsevier
Carbamazepine (CBZ), an antiepileptic drug, is one of the most commonly detected
pharmaceutical drugs in aquatic ecosystems, and is used as a marker of urban pollution …

Environmental risk assessment of widely used anticancer drugs (5-fluorouracil, cisplatin, etoposide, imatinib mesylate)

M Mišík, M Filipic, A Nersesyan, M Kundi, M Isidori… - Water research, 2019 - Elsevier
Anticancer drugs are among the most toxic chemicals, which are commercially produced;
therefore, their release in aquatic ecosystems raised concerns in regard to potential adverse …

The antineoplastic drugs cyclophosphamide and cisplatin in the aquatic environment–Review

V Queirós, UM Azeiteiro, AMVM Soares… - Journal of Hazardous …, 2021 - Elsevier
Abstract Cyclophosphamide (CP) and Cisplatin (CDDP) are antineoplastic drugs widely
used in the treatment of neoplastic diseases that have been detected in the aquatic …

Laccase as an efficacious approach to remove anticancer drugs: A study of doxorubicin degradation, kinetic parameters, and toxicity assessment

M Kelbert, CS Pereira, NA Daronch, K Cesca… - Journal of hazardous …, 2021 - Elsevier
The degradation of an anticancer drug by laccase was investigated for the first time, bringing
a new approach to treat these hazardous substances through the direct enzymatic …

The role of bicarbonate anions in methotrexate degradation via UV/TiO2: mechanisms, reactivity and increased toxicity

WWP Lai, MH Hsu, AYC Lin - Water research, 2017 - Elsevier
Abstract Bicarbonate anion (HCO 3−) is a major constituent in wastewater and natural water
matrices, and the aim of this study was to investigate its roles in the degradation of the …

Cytotoxicity and genotoxicity of anticancer drug residues and their mixtures in experimental model with zebrafish liver cells

M Novak, B Žegura, B Modic, E Heath… - Science of the Total …, 2017 - Elsevier
Anticancer drugs enter aquatic environment predominantly via hospital and municipal
wastewater effluents where they may, due to their genotoxic potential, cause adverse …