Friend or foe? Defining the role of glutamate in aging and Alzheimer's disease
Aging is a naturally occurring decline of physiological processes and biological pathways
that affects both the structural and functional integrity of the body and brain. These …
that affects both the structural and functional integrity of the body and brain. These …
[HTML][HTML] Chemical exchange saturation transfer magnetic resonance imaging and its main and potential applications in pre-clinical and clinical studies
W Dou, CYE Lin, H Ding, Y Shen, C Dou… - … imaging in medicine …, 2019 - ncbi.nlm.nih.gov
Chemical exchange saturation transfer (CEST) imaging is a novel contrast mechanism,
relying on the exchange between mobile protons in amide (-NH), amine (-NH 2) and …
relying on the exchange between mobile protons in amide (-NH), amine (-NH 2) and …
[HTML][HTML] Integrating 1H MRS and deuterium labeled glucose for mapping the dynamics of neural metabolism in humans
In the technique presented here, dubbed 'qMRS', we quantify the change in 1 H MRS signal
following administration of 2 H-labeled glucose. As in recent human DMRS studies, we …
following administration of 2 H-labeled glucose. As in recent human DMRS studies, we …
Hyperpolarized MRI, functional MRI, MR spectroscopy and CEST to provide metabolic information in vivo
Access to metabolic information in vivo using magnetic resonance (MR) technologies has
generally been the niche of MR spectroscopy (MRS) and spectroscopic imaging (MRSI) …
generally been the niche of MR spectroscopy (MRS) and spectroscopic imaging (MRSI) …
A quantitative meta-analysis of brain glutamate metabolites in aging
Glutamate (Glu) is a key molecule in cellular metabolism, the most abundant excitatory
neurotransmitter in the brain, and the principal neurotransmitter of cortical efferents …
neurotransmitter in the brain, and the principal neurotransmitter of cortical efferents …
Glutamate‐weighted CEST (gluCEST) imaging for mapping neurometabolism: An update on the state of the art and emerging findings from in vivo applications
Glutamate is the primary excitatory neurotransmitter in the mammalian central nervous
system. As such, its proper regulation is essential to the healthy function of the human brain …
system. As such, its proper regulation is essential to the healthy function of the human brain …
Application of 7T MRS to high-grade gliomas
L McCarthy, G Verma, G Hangel… - American Journal …, 2022 - Am Soc Neuroradiology
MRS, including single-voxel spectroscopy and MR spectroscopic imaging, captures
metabolites in high-grade gliomas. Emerging evidence indicates that 7T MRS may be more …
metabolites in high-grade gliomas. Emerging evidence indicates that 7T MRS may be more …
Accelerating GluCEST imaging using deep learning for B0 correction
Purpose Glutamate weighted Chemical Exchange Saturation Transfer (GluCEST) MRI is a
noninvasive technique for mapping parenchymal glutamate in the brain. Because of the …
noninvasive technique for mapping parenchymal glutamate in the brain. Because of the …
Emerging MR imaging and spectroscopic methods to study brain tumor metabolism
Proton magnetic resonance spectroscopy (1H-MRS) provides a non-invasive biochemical
profile of brain tumors. The conventional 1H-MRS methods present a few challenges mainly …
profile of brain tumors. The conventional 1H-MRS methods present a few challenges mainly …
Evaluating the feasibility of creatine‐weighted CEST MRI in human brain at 7 T using a Z‐spectral fitting approach
The current study aims to evaluate the feasibility of creatine (Cr) chemical exchange
saturation transfer (CEST)‐weighted MRI at 7 T in the human brain by optimizing the …
saturation transfer (CEST)‐weighted MRI at 7 T in the human brain by optimizing the …