General anesthesia consists of amnesia, hypnosis, analgesia, and areflexia. Of these, the
mechanism of hypnosis, or loss of consciousness, has been the most elusive, yet a …

Background Environmental noise pollution is regarded as a general stressor. Noise levels
frequently exceed recommended noise levels by the World Health Organization in hospitals …

Background Mechanisms of anesthesia-induced loss of consciousness remain poorly
understood. Resting-state functional magnetic resonance imaging allows investigating …

While ubiquitous, pharmacological manipulation of consciousness remains poorly defined
and incompletely understood. This retards anesthetic drug development, confounds …

Intrinsic cortical dynamics modulates the processing of sensory information and therefore
may be critical for conscious perception [1–3]. We tested this hypothesis by …

To date, the majority of neurovascular coupling studies focused on the thalamic afferents'
activity in layer IV and the corresponding large spiking activity as responsible for functional …

Background Recent studies have been shown that functional connectivity of cerebral areas
is not a static phenomenon, but exhibits spontaneous fluctuations over time. There is …

The mechanism of loss of consciousness (LOC) under anesthesia is unknown. Because
consciousness depends on activity in the cortico-thalamic network, anesthetic actions on this …

Background The extent to which complex auditory stimuli are processed and differentiated
during general anesthesia is unknown. The authors used blood oxygenation level …

Energetics of resting and evoked fMRI signals were related to localized ensemble firing
rates (ν) measured by electrophysiology in rats. Two different unstimulated, or baseline …