Advances in biomaterials and technologies for vascular embolization
Minimally invasive transcatheter embolization is a common nonsurgical procedure in
interventional radiology used for the deliberate occlusion of blood vessels for the treatment …
interventional radiology used for the deliberate occlusion of blood vessels for the treatment …
Clinically established biodegradable long acting injectables: an industry perspective
CI Nkanga, A Fisch, M Rad-Malekshahi… - Advanced drug delivery …, 2020 - Elsevier
Long acting injectable formulations have been developed to sustain the action of drugs in
the body over desired periods of time. These delivery platforms have been utilized for both …
the body over desired periods of time. These delivery platforms have been utilized for both …
Basics of dermal filler rheology
S Pierre, S Liew, A Bernardin - Dermatologic surgery, 2015 - journals.lww.com
BACKGROUND Hyaluronic acid injectable fillers are the most widely used dermal fillers to
treat facial volume deficits, providing long-term facial aesthetic enhancement outcomes for …
treat facial volume deficits, providing long-term facial aesthetic enhancement outcomes for …
High-concentration protein formulations: how high is high?
P Garidel, AB Kuhn, LV Schäfer… - European Journal of …, 2017 - Elsevier
High-concentration protein formulation (HCPF) is a term that is used to describe protein
formulations, mostly monoclonal antibody (mAb) drugs, at high protein concentration. The …
formulations, mostly monoclonal antibody (mAb) drugs, at high protein concentration. The …
Mucoadhesive chitosan hydrogels as rectal drug delivery vessels to treat ulcerative colitis
J Xu, M Tam, S Samaei, S Lerouge, J Barralet… - Acta biomaterialia, 2017 - Elsevier
Mucoadhesive drug delivery systems stick to mucosal tissues and prolong the local retention
time of drugs. Since the colon is covered by a mucosal layer, mucoadhesive rectal …
time of drugs. Since the colon is covered by a mucosal layer, mucoadhesive rectal …
Injectable gelatin microgel-based composite ink for 3D bioprinting in air
K Song, AM Compaan, W Chai… - ACS applied materials & …, 2020 - ACS Publications
Injectable hydrogels have attracted much attention in tissue engineering and regenerative
medicine for their capability to replace implantation surgeries with a minimally invasive …
medicine for their capability to replace implantation surgeries with a minimally invasive …
Silk-elastinlike protein-based hydrogels for drug delivery and embolization
E Griswold, J Cappello, H Ghandehari - Advanced Drug Delivery Reviews, 2022 - Elsevier
Abstract Silk-Elastinlike Protein-Based Polymers (SELPs) can form thermoresponsive
hydrogels that allow for the generation of in-situ drug delivery matrices. They are produced …
hydrogels that allow for the generation of in-situ drug delivery matrices. They are produced …
Current state and opportunities with long-acting injectables: industry perspectives from the innovation and quality consortium “long-acting injectables” working group
A Bauer, P Berben, SS Chakravarthi… - Pharmaceutical …, 2023 - Springer
Long-acting injectable (LAI) formulations can provide several advantages over the more
traditional oral formulation as drug product opportunities. LAI formulations can achieve …
traditional oral formulation as drug product opportunities. LAI formulations can achieve …
Integrated data-driven modeling and experimental optimization of granular hydrogel matrices
Granular hydrogel matrices have emerged as promising candidates for cell encapsulation,
bioprinting, and tissue engineering. However, it remains challenging to design and optimize …
bioprinting, and tissue engineering. However, it remains challenging to design and optimize …
Modeling, design, and machine learning-based framework for optimal injectability of microparticle-based drug formulations
Inefficient injection of microparticles through conventional hypodermic needles can impose
serious challenges on clinical translation of biopharmaceutical drugs and microparticle …
serious challenges on clinical translation of biopharmaceutical drugs and microparticle …