Disruptions of circadian rhythms and sleep cycles are common among neurodegenerative
diseases and can occur at multiple levels. Accumulating evidence reveals a bidirectional …

The brain lacks a classic lymphatic drainage system. How it is cleansed of damaged
proteins, cellular debris, and molecular by-products has remained a mystery for decades …

Introduction: Insomnia and circadian rhythm disorders, such as the delayed sleep phase
syndrome, are frequent in psychiatric disorders and their evaluation and management in …

Background The proportion of the world's elderly population continues to rise, and the
treatment and improvement of neurodegenerative diseases have become issue of public …

Alzheimer's disease (AD) is the most frequent type of dementia characterized by the
deposition of amyloid beta (Aβ) plaque and tau-neurofibrillary tangles (TNTs) in the brain …

Dementia is the seventh leading cause of mortality, and a major source of disability and
dependency in older individuals globally. Cognitive decline (and, to a lesser extent, normal …

Abstract Study Objectives To compare the 24-hour sleep assessment capabilities of two
contactless sleep technologies (CSTs) to actigraphy in community-dwelling older adults …

Study Objectives: Sleep disturbances are common in people with Alzheimer's disease (AD),
and a reduction in slow-wave activity is the most striking underlying change. Acoustic …

Dementia is a syndrome characterized by cognitive decline and functional impairment that
encompasses many different specific diseases. Alzheimer's disease (AD) is the most …

There has been ample research showing that insomnia is a potential trigger of depression
as well as a symptom of depression. These two factors contribute to behavioural problems …