Hormonal treatments for major depressive disorder: state of the art
Major depressive disorder is a common psychiatric disorder associated with marked
suffering, morbidity, mortality, and cost. The World Health Organization projects that by 2030 …
suffering, morbidity, mortality, and cost. The World Health Organization projects that by 2030 …
Altering the course of schizophrenia: progress and perspectives
MJ Millan, A Andrieux, G Bartzokis… - Nature reviews Drug …, 2016 - nature.com
Despite a lack of recent progress in the treatment of schizophrenia, our understanding of its
genetic and environmental causes has considerably improved, and their relationship to …
genetic and environmental causes has considerably improved, and their relationship to …
More than a marker: potential pathogenic functions of MAP2
RA DeGiosio, MJ Grubisha, ML MacDonald… - Frontiers in molecular …, 2022 - frontiersin.org
Microtubule-associated protein 2 (MAP2) is the predominant cytoskeletal regulator within
neuronal dendrites, abundant and specific enough to serve as a robust somatodendritic …
neuronal dendrites, abundant and specific enough to serve as a robust somatodendritic …
Efficacy and safety of anti-inflammatory agents in treatment of psychotic disorders–A comprehensive systematic review and meta-analysis
R Jeppesen, RHB Christensen, EMJ Pedersen… - Brain, behavior, and …, 2020 - Elsevier
Objective Antipsychotic effects of immunomodulating drugs have been suggested; however,
a thorough, comprehensive meta-analysis on the effect and safety of anti-inflammatory add …
a thorough, comprehensive meta-analysis on the effect and safety of anti-inflammatory add …
Adjunctive use of anti-inflammatory drugs for schizophrenia: a meta-analytic investigation of randomized controlled trials
Objective: Recent evidence suggests that adjuvant anti-inflammatory agents could improve
the symptoms of patients with schizophrenia. However, the effects of the adjuvant anti …
the symptoms of patients with schizophrenia. However, the effects of the adjuvant anti …
Cognitive deficit in schizophrenia: from etiology to novel treatments
AL Martínez, J Brea, S Rico, MT De los Frailes… - International journal of …, 2021 - mdpi.com
Schizophrenia is a major mental illness characterized by positive and negative symptoms,
and by cognitive deficit. Although cognitive impairment is disabling for patients, it has been …
and by cognitive deficit. Although cognitive impairment is disabling for patients, it has been …
Early interventions in risk groups for schizophrenia: what are we waiting for?
Intervention strategies in adolescents at ultra high-risk (UHR) for psychosis are promising for
reducing conversion to overt illness, but have only limited impact on functional outcome …
reducing conversion to overt illness, but have only limited impact on functional outcome …
Neurosteroid actions in memory and neurologic/neuropsychiatric disorders
Memory dysfunction is a symptomatic feature of many neurologic and neuropsychiatric
disorders; however, the basic underlying mechanisms of memory and altered states of …
disorders; however, the basic underlying mechanisms of memory and altered states of …
Neurosteroids and potential therapeutics: focus on pregnenolone
M Vallée - The Journal of steroid biochemistry and molecular …, 2016 - Elsevier
Considerable evidence from preclinical and clinical studies shows that steroids and in
particular neurosteroids are important endogenous modulators of several brain-related …
particular neurosteroids are important endogenous modulators of several brain-related …
Multimodal electrophysiological analyses reveal that reduced synaptic excitatory neurotransmission underlies seizures in a model of NMDAR antibody-mediated …
Seizures are a prominent feature in N-Methyl-D-Aspartate receptor antibody (NMDAR
antibody) encephalitis, a distinct neuro-immunological disorder in which specific human …
antibody) encephalitis, a distinct neuro-immunological disorder in which specific human …