Objectives To describe the methodological characteristics of mediation analyses (MAs)
reported in recent randomized controlled trials (RCTs) and to propose recommendations on …

The rates of asthma and obesity are increasing concurrently in the United States.
Epidemiologic studies demonstrate that the incidence of asthma increases with obesity …

Abstract Purpose of Review Rising costs and increasing morbidity makes the identification
and treatment of high-risk asthma phenotypes important. In this review, we outline the …

The increasing knowledge of the mechanisms involved in metabolism is shifting the
paradigms by which the pathophysiology of many pulmonary diseases is understood …

Background The dominant allergen in cat dander, Felis domesticus allergen 1 (Fel d 1), is a
persistent trigger for allergic rhinitis and asthma symptoms. Objective We evaluated the …

Obesity and asthma are global public health problems. Obesity-related asthma is a special
phenotype of asthma with a complex pathogenesis. Its occurrence and development are …

Background We assessed the efficacy of the licensed mepolizumab dose (100 mg
subcutaneously [SC]) in patients with severe eosinophilic asthma according to body …

Asthma is a respiratory disorder with considerable heterogeneity in aetiology, triggers,
clinical characteristics and response to therapy. This diversity reflects different inflammatory …

Obesity is a major risk factor for the development of asthma, and the prevalence of obesity is
higher in people with asthma than in the general population. Obese people often have …

Abstract Purpose of Review Three biologics targeting type 2 inflammation have been
approved for the treatment of severe and uncontrolled chronic rhinosinusitis with nasal …