The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …

The transient receptor potential (TRP) superfamily consists of a large number of cation
channels that are mostly permeable to both monovalent and divalent cations. The 28 …

Vital bleaching procedures are a popular means of improving the appearance of discolored
teeth. There is a wide array of whitening products for home and dental office use; all involves …

Mechanisms of inflammatory pain are not fully understood. We investigated the role of
TRPV1 (transient receptor potential subtype V1) and TNF-α, two critical mediators for …

Introduction Although many clinical studies have reported on the prevalence of dental pain,
far fewer studies have focused on the mechanisms of dental pain. This is an important gap …

Peripheral detection of nociceptive and painful stimuli by sensory neurons involves a
complex repertoire of molecular detectors and/or transducers on distinct subsets of nerve …

Specialized receptors belonging to the transient receptor potential (TRP) family of ligand-
gated ion channels constitute the critical detectors and transducers of pain-causing stimuli …

Tooth sensitivity is a common dental pain condition where sufferers experience brief
episodes of sharp well‐localized pain when their teeth are subjected innocuous stimuli such …

Background: Cisplatin is primarily used for treatment of ovarian and testicular cancer.
Oxaliplatin is the only effective treatment for metastatic colorectal cancer. Both are known to …

Sensory nerves detect an extensive array of somatosensory stimuli, including environmental
temperatures. Despite activating only a small cohort of sensory neurons, cold temperatures …