HSV-1 cytoplasmic envelopment and egress

I Ahmad, DW Wilson - International journal of molecular sciences, 2020 - mdpi.com
Herpes simplex virus type 1 (HSV-1) is a structurally complex enveloped dsDNA virus that
has evolved to replicate in human neurons and epithelia. Viral gene expression, DNA …

The multifaceted interactions between pathogens and host ESCRT machinery

Y Rivera-Cuevas, VB Carruthers - PLoS Pathogens, 2023 - journals.plos.org
The Endosomal Sorting Complex Required for Transport (ESCRT) machinery consists of
multiple protein complexes that coordinate vesicle budding away from the host cytosol …

The interplay between ESCRT and viral factors in the enveloped virus life cycle

B Meng, AML Lever - Viruses, 2021 - mdpi.com
Viruses are obligate parasites that rely on host cellular factors to replicate and spread. The
endosomal sorting complexes required for transport (ESCRT) system, which is classically …

[HTML][HTML] Virus budding

L Rheinemann, WI Sundquist - Encyclopedia of virology, 2021 - ncbi.nlm.nih.gov
Enveloped viruses exit producer cells and acquire their external lipid envelopes by budding
through limiting cellular membranes. Most viruses encode multifunctional structural proteins …

The Knowns and unknowns of Herpesvirus nuclear egress

BG Klupp, TC Mettenleiter - Annual Review of Virology, 2023 - annualreviews.org
Nuclear egress of herpesvirus capsids across the intact nuclear envelope is an exceptional
vesicle-mediated nucleocytoplasmic translocation resulting in the delivery of herpesvirus …

The human cytomegalovirus decathlon: Ten critical replication events provide opportunities for restriction

DL Turner, RA Mathias - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
Human cytomegalovirus (HCMV) is a ubiquitous human pathogen that can cause severe
disease in immunocompromised individuals, transplant recipients, and to the developing …

Why cells and viruses cannot survive without an ESCRT

A Calistri, A Reale, G Palù, C Parolin - Cells, 2021 - mdpi.com
Intracellular organelles enwrapped in membranes along with a complex network of vesicles
trafficking in, out and inside the cellular environment are one of the main features of …

Functions of the UL51 protein during the herpesvirus life cycle

X Liu, M Wang, A Cheng, Q Yang, B Tian… - Frontiers in …, 2024 - frontiersin.org
The herpesvirus UL51 protein is a multifunctional tegument protein involved in the
regulation of multiple aspects of the viral life cycle. This article reviews the biological …

Oropouche virus glycoprotein topology and cellular requirements for glycoprotein secretion

NS Barbosa, JO Concha, LLP Dasilva… - Journal of …, 2023 - Am Soc Microbiol
Oropouche virus (OROV; genus Orthobunyavirus) is the etiological agent of Oropouche
fever, a debilitating febrile illness common in South America. We used recombinant …

The precise function of alphaherpesvirus tegument proteins and their interactions during the viral life cycle

Y Cui, M Wang, A Cheng, W Zhang, Q Yang… - Frontiers in …, 2024 - frontiersin.org
Alphaherpesvirus is a widespread pathogen that causes diverse diseases in humans and
animals and can severely damage host health. Alphaherpesvirus particles comprise a DNA …