A Broad Light‐Harvesting Conjugated Oligoelectrolyte Enables Photocatalytic Nitrogen Fixation in a Bacterial Biohybrid

Z Chen, G Quek, JY Zhu, SJW Chan… - Angewandte …, 2023 - Wiley Online Library
We report a rationally designed membrane‐intercalating conjugated oligoelectrolyte (COE),
namely COE‐IC, which endows aerobic N2‐fixing bacteria Azotobacter vinelandii with a …

Real-Time Monitoring of Mitochondrial Damage Using Conjugated Oligoelectrolytes

SJW Chan, JY Zhu, WW Mia Soh… - Journal of the American …, 2023 - ACS Publications
Conjugated oligoelectrolytes (COEs) comprise a class of fluorescent reporters with tunable
optical properties and lipid bilayer affinity. These molecules have proven effective in a range …

Engineering of exosome-liposome hybrid-based theranostic nanomedicines for NIR-II fluorescence imaging-guided and targeted NIR-II photothermal therapy of …

Y Liu, M Li, J Gu, H Huang, H Xie, C Yu, S Roy… - Colloids and Surfaces B …, 2025 - Elsevier
Exosome-liposome hybrid-based vehicles (ELV) are promising carriers for cancer treatment,
but there are rare efficient theranostic probes to label their lipid bilayer membrane for …

Photophysics of Conjugated Oligoelectrolytes Relevant to Two‐Photon Fluorescence‐Lifetime Imaging Microscopy

JY Zhu, A Mikhailovsky, SCJ Wei… - Advanced Functional …, 2023 - Wiley Online Library
Conjugated oligoelectrolytes (COEs) comprise a class of cell‐membrane intercalating
molecules that serve as effective optical reporters. However, little is known about the …

Biomimetic Nanovesicles Synergize with Short-Term Fasting for Enhanced Chemotherapy of Triple-Negative Breast Cancer

ST Chiang, Q Chen, T Han, C Qian, X Shen, Y Lin… - ACS …, 2024 - ACS Publications
Triple-negative breast cancer (TNBC) is the most aggressive and lethal subtype of breast
cancer among women. Chemotherapy acts as the standard regimen for TNBC treatment but …

Molecular Design of a Diketopyrrolopyrrole Conjugated Oligoelectrolyte Capable of Imaging Intracellular Vesicle Membrane Dynamics

SJW Chan, JY Zhu, BRP Yip… - Advanced …, 2024 - Wiley Online Library
Conjugated oligoelectrolytes (COEs) are lipid bilayer spanning optical reporters that hold
promise for delineating spatiotemporal changes in subcellular compartments. However, their …

Analysis of Individual Viral Particles by Flow Virometry

CO Tabler, JC Tilton - Viruses, 2024 - mdpi.com
This review focuses on the emerging field of flow virometry, the study and characterization of
individual viral particles using flow cytometry instruments and protocols optimized for the …

[HTML][HTML] Molecular orientation and optimization of membrane dyes based on conjugated oligoelectrolytes

JY Zhu, GC Bazan - Cell Reports Physical Science, 2023 - cell.com
Conjugated oligoelectrolytes (COEs) are amphiphilic, fluorogenic molecules that
spontaneously associate with lipid bilayer membranes and are gaining attention as …

NIR‐II Conjugated Electrolytes as Biomimetics of Lipid Bilayers for In Vivo Liposome Tracking

Y Meng, J Gao, P Zhou, X Qin, M Tian… - Angewandte Chemie …, 2024 - Wiley Online Library
Liposomes serve as promising and versatile vehicles for drug delivery. Tracking these
nanosized vesicles, particularly in vivo, is crucial for understanding their pharmacokinetics …

An ex vivo model of interactions between extracellular vesicles and peripheral mononuclear blood cells in whole blood

BV Rodriguez, Y Wen, EN Shirk… - Journal of …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) can be loaded with therapeutic cargo and engineered for
retention by specific body sites; therefore, they have great potential for targeted delivery of …