Functionalizing DNA origami to investigate and interact with biological systems
DNA origami has emerged as a powerful method to generate DNA nanostructures with
dynamic properties and nanoscale control. These nanostructures enable complex …
dynamic properties and nanoscale control. These nanostructures enable complex …
Nanotechnology-based strategies against SARS-CoV-2 variants
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has already infected more
than 500 million people globally (as of May 2022), creating the coronavirus disease 2019 …
than 500 million people globally (as of May 2022), creating the coronavirus disease 2019 …
Gene-encoding DNA origami for mammalian cell expression
JA Kretzmann, A Liedl, A Monferrer… - Nature …, 2023 - nature.com
DNA origami may enable more versatile gene delivery applications through its ability to
create custom nanoscale objects with specific targeting, cell-invading, and intracellular …
create custom nanoscale objects with specific targeting, cell-invading, and intracellular …
Multi-micron crisscross structures grown from DNA-origami slats
Living systems achieve robust self-assembly across a wide range of length scales. In the
synthetic realm, nanofabrication strategies such as DNA origami have enabled robust self …
synthetic realm, nanofabrication strategies such as DNA origami have enabled robust self …
Harnessing a paper-folding mechanism for reconfigurable DNA origami
The paper-folding mechanism has been widely adopted in building of reconfigurable
macroscale systems because of its unique capabilities and advantages in programming …
macroscale systems because of its unique capabilities and advantages in programming …
Net-shaped DNA nanostructures designed for rapid/sensitive detection and potential inhibition of the SARS-CoV-2 virus
We present a net-shaped DNA nanostructure (called “DNA Net” herein) design strategy for
selective recognition and high-affinity capture of intact SARS-CoV-2 virions through spatial …
selective recognition and high-affinity capture of intact SARS-CoV-2 virions through spatial …
Spatially patterned neutralizing icosahedral DNA nanocage for efficient SARS-CoV-2 blocking
J Zhang, Y Xu, Y Huang, M Sun, S Liu… - Journal of the …, 2022 - ACS Publications
Broad-spectrum anti-SARS-CoV-2 strategies that can inhibit the infection of wild-type and
mutant strains would alleviate their threats to global public health. Here, we propose an …
mutant strains would alleviate their threats to global public health. Here, we propose an …
Programmable self-assembly of nanoplates into bicontinuous nanostructures
Self-assembly is the process by which individual components arrange themselves into an
ordered structure by changing the shapes, components, and interactions. It has enabled us …
ordered structure by changing the shapes, components, and interactions. It has enabled us …
Hybrid nanostructures: Versatile systems for biomedical applications
Hybrid nanostructures are nanocomposites constructed from at least two different types of
materials to imbibe the individual advantages while overcoming individual shortcomings …
materials to imbibe the individual advantages while overcoming individual shortcomings …
Symmetry-guided inverse design of self-assembling multiscale DNA origami tilings
Recent advances enable the creation of nanoscale building blocks with complex geometries
and interaction specificities for self-assembly. This nearly boundless design space …
and interaction specificities for self-assembly. This nearly boundless design space …