Functionalizing DNA origami to investigate and interact with biological systems

GA Knappe, EC Wamhoff, M Bathe - Nature Reviews Materials, 2023 - nature.com
DNA origami has emerged as a powerful method to generate DNA nanostructures with
dynamic properties and nanoscale control. These nanostructures enable complex …

Nanotechnology-based strategies against SARS-CoV-2 variants

X Huang, E Kon, X Han, X Zhang, N Kong… - Nature …, 2022 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has already infected more
than 500 million people globally (as of May 2022), creating the coronavirus disease 2019 …

Gene-encoding DNA origami for mammalian cell expression

JA Kretzmann, A Liedl, A Monferrer… - Nature …, 2023 - nature.com
DNA origami may enable more versatile gene delivery applications through its ability to
create custom nanoscale objects with specific targeting, cell-invading, and intracellular …

Multi-micron crisscross structures grown from DNA-origami slats

CM Wintersinger, D Minev, A Ershova… - Nature …, 2023 - nature.com
Living systems achieve robust self-assembly across a wide range of length scales. In the
synthetic realm, nanofabrication strategies such as DNA origami have enabled robust self …

Harnessing a paper-folding mechanism for reconfigurable DNA origami

M Kim, C Lee, K Jeon, JY Lee, YJ Kim, JG Lee, H Kim… - Nature, 2023 - nature.com
The paper-folding mechanism has been widely adopted in building of reconfigurable
macroscale systems because of its unique capabilities and advantages in programming …

Net-shaped DNA nanostructures designed for rapid/sensitive detection and potential inhibition of the SARS-CoV-2 virus

N Chauhan, Y Xiong, S Ren, A Dwivedy… - Journal of the …, 2022 - ACS Publications
We present a net-shaped DNA nanostructure (called “DNA Net” herein) design strategy for
selective recognition and high-affinity capture of intact SARS-CoV-2 virions through spatial …

Spatially patterned neutralizing icosahedral DNA nanocage for efficient SARS-CoV-2 blocking

J Zhang, Y Xu, Y Huang, M Sun, S Liu… - Journal of the …, 2022 - ACS Publications
Broad-spectrum anti-SARS-CoV-2 strategies that can inhibit the infection of wild-type and
mutant strains would alleviate their threats to global public health. Here, we propose an …

Programmable self-assembly of nanoplates into bicontinuous nanostructures

H Tanaka, T Dotera, ST Hyde - ACS nano, 2023 - ACS Publications
Self-assembly is the process by which individual components arrange themselves into an
ordered structure by changing the shapes, components, and interactions. It has enabled us …

Hybrid nanostructures: Versatile systems for biomedical applications

S Mehta, A Suresh, Y Nayak, R Narayan… - Coordination Chemistry …, 2022 - Elsevier
Hybrid nanostructures are nanocomposites constructed from at least two different types of
materials to imbibe the individual advantages while overcoming individual shortcomings …

Symmetry-guided inverse design of self-assembling multiscale DNA origami tilings

D Hayakawa, TE Videbæk, GM Grason, WB Rogers - ACS nano, 2024 - ACS Publications
Recent advances enable the creation of nanoscale building blocks with complex geometries
and interaction specificities for self-assembly. This nearly boundless design space …