Opioid-induced bowel dysfunction: pathophysiology and potential new therapies

A Kurz, DI Sessler - Drugs, 2003 - Springer
Opioid treatment for postoperative or chronic pain is frequently associated with adverse
effects, the most common being dose-limiting and debilitating bowel dysfunction …

Incidence, prevalence, and management of opioid bowel dysfunction

M Pappagallo - The American journal of surgery, 2001 - Elsevier
Opioid bowel dysfunction (OBD) is a common adverse effect associated with opioid therapy.
OBD is commonly described as constipation; however, it is a constellation of adverse …

[图书][B] WHO guidelines for the pharmacological and radiotherapeutic management of cancer pain in adults and adolescents

World Health Organization - 2018 - apps.who.int
Cervical cancer is one of the gravest threats to women's lives. It is estimated that over a
million women worldwide currently have cervical cancer. Most of these women have not …

Prospective analysis of safety and efficacy of medical cannabis in large unselected population of patients with cancer

LBL Schleider, R Mechoulam, V Lederman… - European journal of …, 2018 - Elsevier
Background Cancer is a major public health problem as the leading cause of death.
Palliative treatment aimed to alleviate pain and nausea in patients with advanced disease is …

Opioids and the management of chronic severe pain in the elderly: consensus statement of an International Expert Panel with focus on the six clinically most often …

J Pergolizzi, RH Böger, K Budd, A Dahan… - Pain …, 2008 - Wiley Online Library
▪ Abstract Summary of consensus: 1. The use of opioids in cancer pain: The criteria for
selecting analgesics for pain treatment in the elderly include, but are not limited to, overall …

Management of cancer pain

RK Portenoy, P Lesage - The lancet, 1999 - thelancet.com
Patients with cancer have diverse symptoms, impairments in physical and psychological
functioning, and other difficulties that can undermine their quality of life. If inadequately …

Strategies to manage the adverse effects of oral morphine: an evidence-based report

N Cherny, C Ripamonti, J Pereira, C Davis… - Journal of clinical …, 2001 - ascopubs.org
Successful pain management with opioids requires that adequate analgesia be achieved
without excessive adverse effects. By these criteria, a substantial minority of patients treated …

Oral morphine for cancer pain

PJ Wiffen, B Wee, RA Moore - Cochrane Database of …, 2016 - cochranelibrary.com
Background This is the third updated version of a Cochrane review first published in Issue 4,
2003 of The Cochrane Library and first updated in 2007. Morphine has been used for many …

Massage therapy versus simple touch to improve pain and mood in patients with advanced cancer: a randomized trial

JS Kutner, MC Smith, L Corbin, L Hemphill… - Annals of internal …, 2008 - acpjournals.org
Background: Small studies of variable quality suggest that massage therapy may relieve
pain and other symptoms. Objective: To evaluate the efficacy of massage for decreasing …

Opioid-induced bowel dysfunction: pathophysiology and management

C Brock, SS Olesen, AE Olesen, JB Frøkjaer… - Drugs, 2012 - Springer
Opioids are the most commonly prescribed medications to treat severe pain in the Western
world. It has been estimated that up to 90% of American patients presenting to specialized …