Zebrafish as an animal model for biomedical research
Zebrafish have several advantages compared to other vertebrate models used in modeling
human diseases, particularly for large-scale genetic mutant and therapeutic compound …
human diseases, particularly for large-scale genetic mutant and therapeutic compound …
[HTML][HTML] Understanding the habenula: A major node in circuits regulating emotion and motivation
Over the last decade, the understanding of the habenula has rapidly advanced from being
an understudied brain area with the Latin name 'habena” meaning “little rein”, to being …
an understudied brain area with the Latin name 'habena” meaning “little rein”, to being …
Advances in zebrafish as a comprehensive model of mental disorders
L Wang, F Liu, Y Fang, J Ma, J Wang, L Qu… - Depression and …, 2023 - Wiley Online Library
As an important part in international disease, mental disorders seriously damage human
health and social stability, which show the complex pathogenesis and increasing incidence …
health and social stability, which show the complex pathogenesis and increasing incidence …
The zebrafish subcortical social brain as a model for studying social behavior disorders
Y Geng, RT Peterson - Disease models & mechanisms, 2019 - journals.biologists.com
Social behaviors are essential for the survival and reproduction of social species. Many, if
not most, neuropsychiatric disorders in humans are either associated with underlying social …
not most, neuropsychiatric disorders in humans are either associated with underlying social …
The zebrafish for preclinical psilocybin research
In this review, we discuss the possible utility of zebrafish in research on psilocybin, a
psychedelic drug whose recreational use as well as possible clinical application are gaining …
psychedelic drug whose recreational use as well as possible clinical application are gaining …
[HTML][HTML] Deorphanizing FAM19A proteins as pan-neurexin ligands with an unusual biosynthetic binding mechanism
AJ Khalaj, FH Sterky, A Sclip, J Schwenk… - Journal of Cell …, 2020 - rupress.org
Neurexins are presynaptic adhesion molecules that organize synapses by binding to
diverse trans-synaptic ligands, but how neurexins are regulated is incompletely understood …
diverse trans-synaptic ligands, but how neurexins are regulated is incompletely understood …
Impairments of cerebellar structure and function in a zebrafish KO of neuropsychiatric risk gene znf536
Genetic variants in ZNF536 contribute to the risk for neuropsychiatric disorders such as
schizophrenia, autism, and others. The role of this putative transcriptional repressor in brain …
schizophrenia, autism, and others. The role of this putative transcriptional repressor in brain …
Age-dependent effects of chronic stress on zebrafish behavior and regeneration
A Henríquez Martínez, LC Ávila, MA Pulido… - Frontiers in …, 2022 - frontiersin.org
Stress can have a significant impact on many aspects of an organism's physiology and
behavior. However, the relationship between stress and regeneration, and how this …
behavior. However, the relationship between stress and regeneration, and how this …
A Neurexin2aa deficiency results in axon pathfinding defects and increased anxiety in zebrafish
A Koh, S Tao, Y Jing Goh, V Chaganty… - Human molecular …, 2020 - academic.oup.com
Neurexins are presynaptic transmembrane proteins that control synapse activity and are risk
factors for autism spectrum disorder. Zebrafish, a popular model for behavioral studies, has …
factors for autism spectrum disorder. Zebrafish, a popular model for behavioral studies, has …
[HTML][HTML] A review of systems biology research of anxiety disorders
The development of “omic” technologies and deep phenotyping may facilitate a systems
biology approach to understanding anxiety disorders. Systems biology approaches …
biology approach to understanding anxiety disorders. Systems biology approaches …