The benefits and risks of iron supplementation in pregnancy and childhood

MK Georgieff, NF Krebs, SE Cusick - Annual review of nutrition, 2019 - annualreviews.org
Iron deficiency is the most common micronutrient deficiency in the world and
disproportionately affects pregnant women and young children. Iron deficiency has negative …

Choline, neurological development and brain function: a systematic review focusing on the first 1000 days

E Derbyshire, R Obeid - Nutrients, 2020 - mdpi.com
The foundations of neurodevelopment across an individual's lifespan are established in the
first 1000 days of life (2 years). During this period an adequate supply of nutrients are …

Choline: exploring the growing science on its benefits for moms and babies

HW Korsmo, X Jiang, MA Caudill - Nutrients, 2019 - mdpi.com
The importance of ensuring adequate choline intakes during pregnancy is increasingly
recognized. Choline is critical for a number of physiological processes during the prenatal …

The importance of iron deficiency in pregnancy on fetal, neonatal, and infant neurodevelopmental outcomes

MK Georgieff - International Journal of Gynecology & Obstetrics, 2023 - Wiley Online Library
The role of iron in neurodevelopment has long been recognized, and the adverse effects of
early‐life iron deficiency on brain development and subsequent function across the lifespan …

Prenatal and postnatal choline supplementation in fetal alcohol spectrum disorder

AM Ernst, BA Gimbel, E de Water, JK Eckerle… - Nutrients, 2022 - mdpi.com
Fetal alcohol spectrum disorder (FASD) is common and represents a significant public
health burden, yet very few interventions have been tested in FASD. Cognitive deficits are …

Iron deficiency impairs developing hippocampal neuron gene expression, energy metabolism, and dendrite complexity

TW Bastian, WC von Hohenberg… - Developmental …, 2016 - karger.com
Iron deficiency (ID), with and without anemia, affects an estimated 2 billion people
worldwide. ID is particularly deleterious during early-life brain development, leading to long …

The effects of early-life iron deficiency on brain energy metabolism

TW Bastian, R Rao, PV Tran… - Neuroscience …, 2020 - journals.sagepub.com
Iron deficiency (ID) is one of the most prevalent nutritional deficiencies in the world. Iron
deficiency in the late fetal and newborn period causes abnormal cognitive performance and …

[HTML][HTML] Early-life nutritional programming of cognition—the fundamental role of epigenetic mechanisms in mediating the relation between early-life environment and …

L Moody, H Chen, YX Pan - Advances in nutrition, 2017 - Elsevier
The perinatal period is a window of heightened plasticity that lays the groundwork for future
anatomic, physiologic, and behavioral outcomes. During this time, maternal diet plays a …

Fetal iron deficiency induces chromatin remodeling at the Bdnf locus in adult rat hippocampus

PV Tran, BC Kennedy, YC Lien… - American Journal …, 2015 - journals.physiology.org
Fetal and subsequent early postnatal iron deficiency causes persistent impairments in
cognitive and affective behaviors despite prompt postnatal iron repletion. The long-term …

Early-life iron deficiency anemia programs the hippocampal epigenomic landscape

AK Barks, SX Liu, MK Georgieff, TC Hallstrom, PV Tran - Nutrients, 2021 - mdpi.com
Iron deficiency (ID) anemia is the foremost micronutrient deficiency worldwide, affecting
around 40% of pregnant women and young children. ID during the prenatal and early …