Executive summary Every infant, child, and adolescent will experience pain at times
throughout their life. Childhood pain ranges from acute to chronic, and includes procedural …

Central neuropathic pain arises from a lesion or disease of the central somatosensory
nervous system such as brain injury, spinal cord injury, stroke, multiple sclerosis or related …

Non-invasive functional brain imaging is used more than ever to investigate pain in health
and disease, with the prospect of finding new means to alleviate pain and improve patient …

Chronic pain is the greatest source of disability globally and claims related to chronic pain
feature in many insurance and medico-legal cases. Brain imaging (for example, functional …

An overreliance on opioids has impacted all types of pain management, making it
undoubtedly a root cause of the “epidemic” of prescription opioid abuse in the United States …

The aversive experience we call “pain” results from the coordinated activation of multiple
brain areas, commonly described as a “pain matrix”. This is not a fixed arrangement of …

Multiple frontal cortical brain regions have emerged as being important in pain processing,
whether it be integrative, sensory, cognitive, or emotional. One such region, Brodmann Area …

Neural oscillations play an important role in the integration and segregation of brain regions
that are important for brain functions, including pain. Disturbances in oscillatory activity are …

Accumulating evidence has shown that complicated brain systems are involved in the
development and maintenance of chronic low back pain (cLBP), but the association …

Abstract Background and Objective Repetitive transcranial magnetic stimulation (rTMS)
applied to the motor cortex provides supplementary relief for some individuals with chronic …