This Review compiles the evolution, mechanistic understanding, and more recent advances
in enantioselective Pd-catalyzed allylic substitution and decarboxylative and oxidative allylic …

Chiral cyclic structures are found in numerous natural products, pharmaceutical compounds,
and important synthetic intermediates. Asymmetric hydrogenation, allowing for the …

In 2007 the members of the ACS Green Chemistry Institute® Pharmaceutical Roundtable
assembled a list of key green chemistry research areas to both identify transformations that …

A solvent is one key component in a chemical transformation. As a reaction medium it
controls the interactions between reaction partners through heat transfer and intermolecular …

The asymmetric hydrogenation of alkenes using transition metal catalysts continues to be a
growing field and a fundamental tool for organic synthetic chemists. In contrast to, for …

A new organocatalytic transfer hydrogenation strategy for the asymmetric synthesis of 1, 1-
diarylethanes is described. Under mild conditions, a range of 1, 1-diarylethanes substituted …

Discovering efficient methods for gaining access to enantiomerically pure compounds in the
development of pharmaceuticals, agrochemicals, and flavors has been a great challenge for …

The asymmetric hydrogenation of cyclic alkenes lacking coordinating functionality with a C 1-
symmetric bis (imino) pyridine cobalt catalyst is described and has been applied to the …

The success of phosphine-oxazoline ligands (PHOX) inspired the progress in P-oxazoline
ligand families by modifying either the ligand backbone, the electronic and/or steric …

Conspectus Among chiral phosphines, P-stereogenic phosphines provide unparalleled
activity and selectivity and have thus emerged as “state-of-the-art” ligands for asymmetric …