[HTML][HTML] Dopamine: the neuromodulator of long-term synaptic plasticity, reward and movement control

L Speranza, U Di Porzio, D Viggiano, A de Donato… - Cells, 2021 - mdpi.com
Dopamine (DA) is a key neurotransmitter involved in multiple physiological functions
including motor control, modulation of affective and emotional states, reward mechanisms …

[HTML][HTML] Midbrain dopaminergic neurons: a review of the molecular circuitry that regulates their development

SV Hegarty, AM Sullivan, GW O'keeffe - Developmental biology, 2013 - Elsevier
Dopaminergic (DA) neurons of the ventral midbrain (VM) play vital roles in the regulation of
voluntary movement, emotion and reward. They are divided into the A8, A9 and A10 …

Maternal vitamin D deficiency alters the expression of genes involved in dopamine specification in the developing rat mesencephalon

X Cui, M Pelekanos, THJ Burne, JJ McGrath… - Neuroscience …, 2010 - Elsevier
Schizophrenia is a neurodevelopment disorder that is strongly associated with alterations in
dopamine neurotransmission. Common features of animal models of schizophrenia include …

Bdnf gene is a downstream target of Nurr1 transcription factor in rat midbrain neurons in vitro

F Volpicelli, M Caiazzo, D Greco… - Journal of …, 2007 - Wiley Online Library
The transcription factor Nurr1 is essential for the generation of midbrain dopaminergic
neurons (mDA). Only a few Nurr1‐regulated genes have so far been identified and it …

[HTML][HTML] Altered dopamine ontogeny in the developmentally vitamin D deficient rat and its relevance to schizophrenia

JP Kesby, X Cui, THJ Burne, DW Eyles - Frontiers in cellular …, 2013 - frontiersin.org
Schizophrenia is a heterogeneous group of disorders with unknown etiology. Although
abnormalities in multiple neurotransmitter systems have been linked to schizophrenia …

[HTML][HTML] Molecular regulation in dopaminergic neuron development. Cues to unveil molecular pathogenesis and pharmacological targets of neurodegeneration

F Volpicelli, C Perrone-Capano, GC Bellenchi… - International Journal of …, 2020 - mdpi.com
The relatively few dopaminergic neurons in the mammalian brain are mostly located in the
midbrain and regulate many important neural functions, including motor integration …

Gliosis alters expression and uptake of spinal glial amino acid transporters in a mouse neuropathic pain model

C Cavaliere, G Cirillo, MR Bianco, F Rossi… - Neuron glia …, 2007 - cambridge.org
Gliosis is strongly implicated in the development and maintenance of persistent pain states
following chronic constriction injury of the sciatic nerve. Here we demonstrate that in the …

Developmental vitamin D (DVD) deficiency reduces Nurr1 and TH expression in post-mitotic dopamine neurons in rat mesencephalon

W Luan, LA Hammond, E Cotter, GW Osborne… - Molecular …, 2018 - Springer
Developmental vitamin D (DVD) deficiency has been proposed as an important risk factor for
schizophrenia. Our previous study using Sprague Dawley rats found that DVD deficiency …

Nuclear receptor 4A2 and C/EBPβ regulate the parathyroid hormone-mediated transcriptional regulation of the 25-hydroxyvitamin D3-1α-hydroxylase

C Zierold, JA Nehring, HF Deluca - Archives of biochemistry and biophysics, 2007 - Elsevier
1α-Hydroxylase is the enzyme responsible for the production of the active form of vitamin D,
1, 25-dihydroxyvitamin D3. 1α-Hydroxylase, found largely in the kidney, is known to be up …

[HTML][HTML] Nurr1 is not an essential regulator of BDNF in mouse cortical neurons

M Abdollahi, M Fahnestock - International Journal of Molecular Sciences, 2022 - mdpi.com
Nurr1 and brain-derived neurotrophic factor (BDNF) play major roles in cognition. Nurr1
regulates BDNF in midbrain dopaminergic neurons and cerebellar granule cells. Nurr1 and …