Fibronectin structure and composition regulate contextual cell signaling. Recent advances
have been made in understanding fibronectin and its role in tissue organization and repair …

Peripheral nerves injuries result in paralysis, anesthesia and lack of autonomic control of the
affected body areas. After injury, axons distal to the lesion are disconnected from the …

Whereas the central nervous system (CNS) usually cannot regenerate, peripheral nerves
regenerate spontaneously after injury because of a permissive environment and activation …

The peripheral nervous system retains a considerable capacity for regeneration. However,
functional recovery rarely returns to the preinjury level no matter how accurate the nerve …

The neurotrophin family includes NGF, brain-derived neurotrophic factor (BDNF),
neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). Previous studies have demonstrated that …

ABSTRACT A loss of function mutation of the murineα5 integrin gene generated by gene
targeting in embryonic stem cells is a recessive embryonic lethal. The mutant embryos start …

Peripheral nerve regeneration comprises the formation of axonal sprouts, their outgrowth as
regenerating axons and the reinnervation of original targets. This review focuses on the …

Wallerian degeneration is a cascade of stereotypical events in reaction to injury of nerve
fibres. These events consist of cellular and molecular alterations, including macrophage …

In dystrophic mice, a model of merosin-deficient congenital muscular dystrophy, laminin-2
mutations produce peripheral nerve dysmyelination and render Schwann cells unable to …

Diabetic neuropathy is the most common peripheral neuropathy in western countries.
Although every effort has been made to clarify the pathogenic mechanism of diabetic …