Reduction–oxidation (redox) system in radiation-induced normal tissue injury: molecular mechanisms and implications in radiation therapeutics
R Yahyapour, E Motevaseli, A Rezaeyan… - Clinical and …, 2018 - Springer
Every year, millions of cancer patients undergo radiation therapy for treating and destroying
abnormal cell growths within normal cell environmental conditions. Thus, ionizing radiation …
abnormal cell growths within normal cell environmental conditions. Thus, ionizing radiation …
Radiation protection and mitigation by natural antioxidants and flavonoids: implications to radiotherapy and radiation disasters
R Yahyapour, D Shabeeb, M Cheki… - Current molecular …, 2018 - ingentaconnect.com
Background: Nowadays, ionizing radiations are used for various medical and terroristic
aims. These purposes involve exposure to ionizing radiations. Hence, people are at risk for …
aims. These purposes involve exposure to ionizing radiations. Hence, people are at risk for …
Melatonin and cancer: From the promotion of genomic stability to use in cancer treatment
B Farhood, NH Goradel, K Mortezaee… - Journal of cellular …, 2019 - Wiley Online Library
Cancer remains among the most challenging human diseases. Several lines of evidence
suggest that carcinogenesis is a complex process that is initiated by DNA damage …
suggest that carcinogenesis is a complex process that is initiated by DNA damage …
Resveratrol as an adjuvant for normal tissues protection and tumor sensitization
Cancer is one of the most complicated diseases in present-day medical science. Yearly,
several studies suggest various strategies for preventing carcinogenesis. Furthermore …
several studies suggest various strategies for preventing carcinogenesis. Furthermore …
NADPH oxidase as a target for modulation of radiation response; implications to carcinogenesis and radiotherapy
K Mortezaee, NH Goradel, P Amini… - Current molecular …, 2019 - ingentaconnect.com
Background: Radiotherapy is a treatment modality for cancer. For better therapeutic
efficiency, it could be used in combination with surgery, chemotherapy or immunotherapy. In …
efficiency, it could be used in combination with surgery, chemotherapy or immunotherapy. In …
Metformin: Prevention of genomic instability and cancer: A review
The diabetes drug metformin can mitigate the genotoxic effects of cytotoxic agents and has
been proposed to prevent or even cure certain cancers. Metformin reduces DNA damage by …
been proposed to prevent or even cure certain cancers. Metformin reduces DNA damage by …
Oxidative stress as cause, consequence, or biomarker of altered female reproduction and development in the space environment
JG Steller, JR Alberts, AE Ronca - International journal of molecular …, 2018 - mdpi.com
Oxidative stress has been implicated in the pathophysiology of numerous terrestrial disease
processes and associated with morbidity following spaceflight. Furthermore, oxidative stress …
processes and associated with morbidity following spaceflight. Furthermore, oxidative stress …
Intercellular communications-redox interactions in radiation toxicity; potential targets for radiation mitigation
B Farhood, NH Goradel, K Mortezaee… - Journal of cell …, 2019 - Springer
Nowadays, using ionizing radiation (IR) is necessary for clinical, agricultural, nuclear energy
or industrial applications. Accidental exposure to IR after a radiation terror or disaster poses …
or industrial applications. Accidental exposure to IR after a radiation terror or disaster poses …
Evaluating biomarkers to model cancer risk post cosmic ray exposure
DM Sridharan, A Asaithamby, SR Blattnig… - Life sciences in space …, 2016 - Elsevier
Robust predictive models are essential to manage the risk of radiation-induced
carcinogenesis. Chronic exposure to cosmic rays in the context of the complex deep space …
carcinogenesis. Chronic exposure to cosmic rays in the context of the complex deep space …
Novel indications for commonly used medications as radiation protectants in spaceflight
MF McLaughlin, DB Donoviel… - Aerospace medicine and …, 2017 - ingentaconnect.com
BACKGROUND: In the space environment, the traditional radioprotective principles of time,
distance, and shielding become difficult to implement. Additionally, the complex radiation …
distance, and shielding become difficult to implement. Additionally, the complex radiation …