Monocyte chemoattractant protein-1 (MCP-1/CCL2) is renowned for its ability to drive the
chemotaxis of myeloid and lymphoid cells. It orchestrates the migration of these cell types …

Cancer disease describes any pathology involving uncontrolled cell growth. As cells
duplicate, they can remain localized in defined tissues, forming tumor masses and altering …

Macrophages and inflammation play a beneficial role during wound repair with
macrophages regulating a wide range of processes, such as removal of dead cells, debris …

Metastatic disease is the leading cause of death among cancer patients and involves a
complex and inefficient process. Every step of the metastatic process can be rate limiting …

Breast cancer is the most commonly occurring cancer in women of Western countries and is
the leading cause of cancer-related mortality. The breast tumor microenvironment contains …

Macrophages are cells that mediate both innate and adaptive immunity reactions, playing a
major role in both physiological and pathological processes. Systemic SARS-CoV-2 …

Infiltrating tumor-associated macrophages (TAM) are known to impede immunotherapy
against glioblastoma (GBM), however, TAMs are heterogeneous, and there are no clear …

Biodegradability and mechanical properties of magnesium alloys are attractive for
orthopaedic and cardiovascular applications. In order to study their cytotoxicity usually bone …

Macrophages, important cells of innate immunity, are known for their phagocytic activity,
capability for antigen presentation, and flexible phenotypes. Macrophages are found in all …

M2-like polarized tumor-associated macrophages (TAMs) play a pivotal role in promoting
cancer cell growth, invasion, metastasis and angiogenesis. The identification of M2-like …