Engineered Synthetic Matrices for Human Intestinal Organoid Culture and Therapeutic Delivery

A Mulero‐Russe, AJ García - Advanced Materials, 2024 - Wiley Online Library
Human intestinal organoids (HIOs) derived from pluripotent stem cells or adult stem cell
biopsies represent a powerful platform to study human development, drug testing, and …

[HTML][HTML] Recent Advances in Hydrogel Technology in Delivering Mesenchymal Stem Cell for Osteoarthritis Therapy

X Wang, W He, H Huang, J Han, R Wang, H Li, Y Long… - Biomolecules, 2024 - mdpi.com
Osteoarthritis (OA), a chronic joint disease affecting over 500 million individuals globally, is
characterized by the destruction of articular cartilage and joint inflammation. Conventional …

[HTML][HTML] Hydrogel degradation promotes angiogenic and regenerative potential of cell spheroids for wound healing

VL Thai, DH Ramos-Rodriguez, M Mesfin, JK Leach - Materials Today Bio, 2023 - Elsevier
Chronic nonhealing wounds are debilitating and diminish one's quality of life, necessitating
the development of improved strategies for effective treatment. Biomaterial-and cell-based …

Electrospun fibers based anisotropic silk fibroin film with photodynamic antibacterial therapy for S. aureus infected wound healing

J Li, S Zhang, C He, J Ling - International Journal of Biological …, 2024 - Elsevier
Bacterial infection has been regarded as a life-threatening problem in clinic. In addition to
screening of new antibiotics, it is important to develop highly effective antibacterial materials …

[HTML][HTML] Alternative therapeutic strategies in diabetes management

A Annicchiarico, B Barile, C Buccoliero… - World Journal of …, 2024 - ncbi.nlm.nih.gov
Diabetes is a heterogeneous metabolic disease characterized by elevated blood glucose
levels resulting from the destruction or malfunction of pancreatic β cells, insulin resistance in …

Application of Mesenchymal Stem Cells and Exosome alone or Combination Therapy as a Treatment Strategy for Wound Healing

S Nouri, S Shokraneh, P Fatehi Shalamzari… - Cell Biochemistry and …, 2024 - Springer
The process of wound healing consists of multiple phases, and any disruptions in these
phases can lead to the wound becoming chronic and impose heavy financial and …

[HTML][HTML] A Supportive Role of Mesenchymal Stem Cells on Insulin-Producing Langerhans Islets with a Specific Emphasis on The Secretome

RV Sionov, R Ahdut-HaCohen - Biomedicines, 2023 - mdpi.com
Type 1 Diabetes (T1D) is a chronic autoimmune disease characterized by a gradual
destruction of insulin-producing β-cells in the endocrine pancreas due to innate and specific …

A Comprehensive Exploration of Hydrogel Applications in Multi-Stage Skin Wound Healing

Y Lu, Y Wang, J Wang, L Liang, J Li, Y Yu, J Zeng… - Biomaterials …, 2024 - pubs.rsc.org
The hydrogel, as an emerging biomaterial, has found extensive use in the healing of
wounds due to its distinctive physicochemical structure and functional properties. Moreover …

Injectable Oxygen‐Carrying Microsphere Hydrogel for Dynamic Regulation of Redox Microenvironment of Wounds

YJ Fu, RK Wang, CY Ma, LY Wang, SY Long, K Li… - Small, 2024 - Wiley Online Library
The delayed healing of infected wounds can be attributed to the increased production of
reactive oxygen species (ROS) and consequent damages to vascellum and tissue, resulting …

Fast-relaxing hydrogels with reversibly tunable mechanics for dynamic cancer cell culture

YY Khine, H Nguyen, F Afolabi, CC Lin - Biomaterials Advances, 2024 - Elsevier
The mechanics of the tumor microenvironment (TME) significantly impact disease
progression and the efficacy of anti-cancer therapeutics. While it is recognized that …