UroPathogenic Escherichia coli (UPEC) Infections: Virulence Factors, Bladder Responses, Antibiotic, and Non-antibiotic Antimicrobial Strategies
ME Terlizzi, G Gribaudo, ME Maffei - Frontiers in microbiology, 2017 - frontiersin.org
Urinary tract infections (UTIs) are one of the most common pathological conditions in both
community and hospital settings. It has been estimated that about 150 million people …
community and hospital settings. It has been estimated that about 150 million people …
Nonantibiotic prevention and management of recurrent urinary tract infection
N Sihra, A Goodman, R Zakri, A Sahai… - Nature Reviews …, 2018 - nature.com
Urinary tract infections (UTIs) are highly prevalent, lead to considerable patient morbidity,
incur large financial costs to health-care systems and are one of the most common reasons …
incur large financial costs to health-care systems and are one of the most common reasons …
Urinary tract infection: Pathogenicity, antibiotic resistance and development of effective vaccines against Uropathogenic Escherichia coli
Urinary tract infections (UTIs) are recognized as one of the most common infectious
diseases in the world that can be divided to different types. Uropathogenic Escherichia coli …
diseases in the world that can be divided to different types. Uropathogenic Escherichia coli …
The nature of immune responses to urinary tract infections
SN Abraham, Y Miao - Nature Reviews Immunology, 2015 - nature.com
The urinary tract is constantly exposed to microorganisms that inhabit the gastrointestinal
tract, but generally the urinary tract resists infection by gut microorganisms. This resistance …
tract, but generally the urinary tract resists infection by gut microorganisms. This resistance …
Prevention and treatment of uncomplicated lower urinary tract infections in the era of increasing antimicrobial resistance—non-antibiotic approaches: a systemic …
S Wawrysiuk, K Naber, T Rechberger… - Archives of gynecology and …, 2019 - Springer
Abstract Purpose Urinary tract infections (UTIs) are one of the more common infections
encountered in everyday clinical practice. They account for 10–20% of all infections treated …
encountered in everyday clinical practice. They account for 10–20% of all infections treated …
[HTML][HTML] The impact of biological sex on diseases of the urinary tract
L Deltourbe, LL Mariano, TN Hreha, DA Hunstad… - Mucosal …, 2022 - Elsevier
Biological sex, being female or male, broadly influences diverse immune phenotypes,
including immune responses to diseases at mucosal surfaces. Sex hormones, sex …
including immune responses to diseases at mucosal surfaces. Sex hormones, sex …
[HTML][HTML] Estrogen: the necessary evil for human health, and ways to tame it
Estrogen is a pivotal enzyme for survival and health in both genders, though their quantum,
tropism, tissue-specific distribution, and receptor affinity varies with different phases of life …
tropism, tissue-specific distribution, and receptor affinity varies with different phases of life …
Infection in an aging population
KA Kline, DME Bowdish - Current opinion in microbiology, 2016 - Elsevier
Highlights•One third of deaths in adults in the elderly are due to infectious disease.•Changes
in the aging immune response increase the risk of infection in the elderly.•Respiratory …
in the aging immune response increase the risk of infection in the elderly.•Respiratory …
The immune response to infection in the bladder
L Lacerda Mariano, MA Ingersoll - Nature Reviews Urology, 2020 - nature.com
The bladder is continuously protected by passive defences such as a mucus layer,
antimicrobial peptides and secretory immunoglobulins; however, these defences are …
antimicrobial peptides and secretory immunoglobulins; however, these defences are …
Diabetes downregulates the antimicrobial peptide psoriasin and increases E. coli burden in the urinary bladder
S Mohanty, W Kamolvit, A Scheffschick… - Nature …, 2022 - nature.com
Diabetes is known to increase susceptibility to infections, partly due to impaired granulocyte
function and changes in the innate immunity. Here, we investigate the effect of diabetes, and …
function and changes in the innate immunity. Here, we investigate the effect of diabetes, and …