Novel processes associated with the repair of interstrand cross-links derived from abasic sites in duplex DNA: Roles for the base excision repair glycosylase NEIL3 …
NE Price, KS Gates - Chemical Research in Toxicology, 2024 - ACS Publications
Recent studies have defined a novel pathway for the repair of interstrand cross-links derived
from the reaction of an adenine residue with an apurinic/apyrimidinic (AP) site on the …
from the reaction of an adenine residue with an apurinic/apyrimidinic (AP) site on the …
Formation and repair of unavoidable, endogenous interstrand cross-links in cellular DNA
Genome integrity is essential for life and, as a result, DNA repair systems evolved to remove
unavoidable DNA lesions from cellular DNA. Many forms of life possess the capacity to …
unavoidable DNA lesions from cellular DNA. Many forms of life possess the capacity to …
Interstrand cross-link formation involving reaction of a mispaired cytosine residue with an abasic site in duplex DNA
JG Varela, LE Pierce, X Guo, NE Price… - Chemical research in …, 2021 - ACS Publications
The formation of interstrand cross-links in duplex DNA is important in biology, medicine, and
biotechnology. Interstrand cross-links arising from the reaction of the aldehyde residue of an …
biotechnology. Interstrand cross-links arising from the reaction of the aldehyde residue of an …
[HTML][HTML] Crosslinker-modified nucleic acid probes for improved target identification and biomarker detection
J Elskens, A Madder - RSC Chemical Biology, 2021 - pubs.rsc.org
Understanding the intricate interaction pattern of nucleic acids with other molecules is
essential to gain further insight in biological processes and disease mechanisms. To this …
essential to gain further insight in biological processes and disease mechanisms. To this …
Structural studies of an abasic site DNA damage repair and DNA interstrand cross-link formation
B Landová - 2024 - dspace.cuni.cz
DNA damage refers to any alteration or modification in the DNA structure that deviates from
its natural state. Abasic site (Ap site) is one of the most common DNA lesions resulting from …
its natural state. Abasic site (Ap site) is one of the most common DNA lesions resulting from …
Synthesis of DNA duplexes containing site-specific interstrand cross-links via sequential reductive amination reactions involving diamine linkers and abasic sites on …
K Housh, KS Gates - Chemical research in toxicology, 2021 - ACS Publications
Interstrand DNA cross-links are important in biology, medicinal chemistry, and materials
science. Accordingly, methods for the targeted installation of interstrand cross-links in DNA …
science. Accordingly, methods for the targeted installation of interstrand cross-links in DNA …