Mitochondria are essential organelles within the cell where most ATP is produced through
oxidative phosphorylation (OXPHOS). A subset of the genes needed for this process are …

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system. Current treatments are very effective in reducing the neuroinflammatory attack, but …

Background Multiple sclerosis (MS) commonly affects young adults at the ages 20 to 40
years old, but it can onset at each age. Late-onset multiple sclerosis (LOMS) is defined as …

Abstract Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). To date, there is no effective therapeutic approach …

Mitochondria, the organelles that function as the powerhouse of the cell, have been
increasingly linked to the pathogenesis of many neurological disorders, including multiple …

Mitochondria are essential organelles within the cell where most of the energy production
occurs by the oxidative phosphorylation system (OXPHOS). Critical components of the …

Innate immune response is one of our primary defenses against pathogens infection,
although, if dysregulated, it represents the leading cause of chronic tissue inflammation. This …

Objective: To assess the influence of common mitochondrial DNA (mtDNA) sequence
variation on multiple sclerosis (MS) risk in cases and controls part of an international …

Recent studies have linked cell-free mitochondrial DNA (ccf-mtDNA) to neurodegeneration
in both Alzheimer's and Parkinson's disease, raising the possibility that the same …

Induction of protein synthesis by the external delivery of in-vitro transcription-messenger
RNA (IVT-mRNA) has been a useful approach in the realm of cell biology, disease …