Inflammasomes are intracellular multimeric complexes that cleave the precursors of the IL-1
family of cytokines and various proteins, found predominantly in cells of hematopoietic …

Inflammasomes are multimeric protein complexes, sensors of intracellular danger signals,
and crucial components of the innate immune system, with the NLRP3 inflammasome being …

Acute lymphoblastic leukemia (ALL) is the most common hematologic malignancy in
children in childhood. Single-nucleotide polymorphism (SNPs) in key molecules of the …

Besides various infectious and inflammatory complications, recent studies also indicated the
significance of NLRP3 inflammasome in cancer progression and therapy. NLRP3-mediated …

Inflammation is a physiological mechanism of the immune response and has an important
role in maintaining the hematopoietic cell niche in the bone marrow. During this process, the …

The relationship between the IL1B-511C> T (rs16944) polymorphism and the risk of
developing hematologic malignancies remains controversial. Thus, we performed a meta …

Objective: This study was to comprehensively clarify the associations between single
nucleotide polymorphisms (SNPs) in inflammatory genes and the susceptibility to childhood …

Leukemia is a cancer affecting the hematopoietic system with an unclear pathogenesis.
Recent studies suggest a correlation between several long non-coding RNAs (lncRNAs) …

Introduction To investigate the genetic contribution of 24 GWAS-associated polymorphic
gene variants on the development of children's B-lineage acute lymphoblastic leukemia (B …

Acute lymphoblastic leukemia (ALL) is the most common hematologic malignancy and the
leading cause of childhood mortality. Single-nucleotide variants (SNVs) in key molecules of …