The emergence of multi-drug-resistant bacteria is threatening to human health and life
around the world. In particular, methicillin-resistant Staphylococcus aureus (MRSA) causes …

Multidrug‐resistant bacterial infections have become an important cause of clinical death in
the twenty‐first century. Much effort has been made to overcome this challenge. The …

Vancomycin-resistant enterococci (VRE) are the second leading cause of hospital-acquired
infections (HAIs) attributed to a drug-resistant bacterium in the United States, and resistance …

Antibiotic-resistant bacteria represent a serious threat to modern medicine and human life.
Only a minority of antibacterial agents are active against Gram-negative bacteria. Hence, the …

Antibiotic resistance is one of the most important challenges of the 21st century. However,
the growing understanding of bacterial pathogenesis and cell-to-cell communication has …

Background The discovery of antibiotics several decades ago was a defining moment in
history. They were used to treat previously incurable diseases and save many lives …

Candida species are a leading source of healthcare infections globally. The limited number
of antifungal drugs combined with the isolation of Candida species, namely C. albicans and …

Gram-negative bacteria pose a distinctive risk worldwide, especially with the evolution of
major resistance to carbapenems, fluoroquinolones and colistin. Therefore, development of …

Novel benzothiazole‒urea hybrids were designed, synthesized and evaluated their anti-
bacterial activity. They only exhibited anti-bacterial activity against Gram-positive bacteria …

Methicillin-resistant Staphylococcus aureus (MRSA) causes severe public health challenges
throughout the world, and the multi-drug resistance (MDR) of MRSA to antibiotics …