Current Development of Thiazole-Containing Compounds as Potential Antibacterials against Methicillin-Resistant Staphylococcus aureus
H Liu, T Xu, Z Xue, M Huang, T Wang… - ACS Infectious …, 2024 - ACS Publications
The emergence of multi-drug-resistant bacteria is threatening to human health and life
around the world. In particular, methicillin-resistant Staphylococcus aureus (MRSA) causes …
around the world. In particular, methicillin-resistant Staphylococcus aureus (MRSA) causes …
Recent development of pyrimidine‐containing antimicrobial agents
J Zhuang, S Ma - ChemMedChem, 2020 - Wiley Online Library
Multidrug‐resistant bacterial infections have become an important cause of clinical death in
the twenty‐first century. Much effort has been made to overcome this challenge. The …
the twenty‐first century. Much effort has been made to overcome this challenge. The …
Optimization of Acetazolamide-Based Scaffold as Potent Inhibitors of Vancomycin-Resistant Enterococcus
Vancomycin-resistant enterococci (VRE) are the second leading cause of hospital-acquired
infections (HAIs) attributed to a drug-resistant bacterium in the United States, and resistance …
infections (HAIs) attributed to a drug-resistant bacterium in the United States, and resistance …
SAR investigation and optimization of benzimidazole-based derivatives as antimicrobial agents against Gram-negative bacteria
Antibiotic-resistant bacteria represent a serious threat to modern medicine and human life.
Only a minority of antibacterial agents are active against Gram-negative bacteria. Hence, the …
Only a minority of antibacterial agents are active against Gram-negative bacteria. Hence, the …
Bacterial virulence factors: a target for heterocyclic compounds to combat bacterial resistance
Antibiotic resistance is one of the most important challenges of the 21st century. However,
the growing understanding of bacterial pathogenesis and cell-to-cell communication has …
the growing understanding of bacterial pathogenesis and cell-to-cell communication has …
Multidrug-resistant gram-negative organisms: a review of recently approved antibiotics and novel pipeline agents
A Provenzani, AR Hospodar, AL Meyer… - International Journal of …, 2020 - Springer
Background The discovery of antibiotics several decades ago was a defining moment in
history. They were used to treat previously incurable diseases and save many lives …
history. They were used to treat previously incurable diseases and save many lives …
Identification of a Phenylthiazole Small Molecule with Dual Antifungal and Antibiofilm Activity Against Candida albicans and Candida auris
H Mohammad, HE Eldesouky, T Hazbun… - Scientific reports, 2019 - nature.com
Candida species are a leading source of healthcare infections globally. The limited number
of antifungal drugs combined with the isolation of Candida species, namely C. albicans and …
of antifungal drugs combined with the isolation of Candida species, namely C. albicans and …
Development of benzimidazole-based derivatives as antimicrobial agents and their synergistic effect with colistin against gram-negative bacteria
Gram-negative bacteria pose a distinctive risk worldwide, especially with the evolution of
major resistance to carbapenems, fluoroquinolones and colistin. Therefore, development of …
major resistance to carbapenems, fluoroquinolones and colistin. Therefore, development of …
Novel benzothiazole‒urea hybrids: Design, synthesis and biological activity as potent anti-bacterial agents against MRSA
L Zha, Y Xie, C Wu, M Lei, X Lu, W Tang… - European Journal of …, 2022 - Elsevier
Novel benzothiazole‒urea hybrids were designed, synthesized and evaluated their anti-
bacterial activity. They only exhibited anti-bacterial activity against Gram-positive bacteria …
bacterial activity. They only exhibited anti-bacterial activity against Gram-positive bacteria …
2, 4-Diacetylphloroglucinol (DAPG) derivatives rapidly eradicate methicillin-resistant staphylococcus aureus without resistance development by disrupting membrane
Y Zhong, X He, W Tao, J Feng, R Zhang, H Gong… - European Journal of …, 2023 - Elsevier
Methicillin-resistant Staphylococcus aureus (MRSA) causes severe public health challenges
throughout the world, and the multi-drug resistance (MDR) of MRSA to antibiotics …
throughout the world, and the multi-drug resistance (MDR) of MRSA to antibiotics …