The cerebellar involvement in autism spectrum disorders: from the social brain to mouse models
Autism spectrum disorders (ASD) are pervasive neurodevelopmental disorders that include
a variety of forms and clinical phenotypes. This heterogeneity complicates the clinical and …
a variety of forms and clinical phenotypes. This heterogeneity complicates the clinical and …
[HTML][HTML] Characteristics of brains in autism spectrum disorder: structure, function and connectivity across the lifespan
S Ha, IJ Sohn, N Kim, HJ Sim… - Experimental …, 2015 - ncbi.nlm.nih.gov
Autism spectrum disorder (ASD) is a highly prevalent neurodevelopmental disorder
characterized by impaired social communication and restricted and repetitive behaviors …
characterized by impaired social communication and restricted and repetitive behaviors …
The autism brain imaging data exchange: towards a large-scale evaluation of the intrinsic brain architecture in autism
Autism spectrum disorders (ASDs) represent a formidable challenge for psychiatry and
neuroscience because of their high prevalence, lifelong nature, complexity and substantial …
neuroscience because of their high prevalence, lifelong nature, complexity and substantial …
Salience network–based classification and prediction of symptom severity in children with autism
Importance Autism spectrum disorder (ASD) affects 1 in 88 children and is characterized by
a complex phenotype, including social, communicative, and sensorimotor deficits. Autism …
a complex phenotype, including social, communicative, and sensorimotor deficits. Autism …
Mutations in human accelerated regions disrupt cognition and social behavior
Comparative analyses have identified genomic regions potentially involved in human
evolution but do not directly assess function. Human accelerated regions (HARs) represent …
evolution but do not directly assess function. Human accelerated regions (HARs) represent …
Reconceptualizing functional brain connectivity in autism from a developmental perspective
While there is almost universal agreement amongst researchers that autism is associated
with alterations in brain connectivity, the precise nature of these alterations continues to be …
with alterations in brain connectivity, the precise nature of these alterations continues to be …
Autism as a neural systems disorder: a theory of frontal-posterior underconnectivity
The underconnectivity theory of autism attributes the disorder to lower anatomical and
functional systems connectivity between frontal and more posterior cortical processing. Here …
functional systems connectivity between frontal and more posterior cortical processing. Here …
Increased functional connectivity between subcortical and cortical resting-state networks in autism spectrum disorder
Importance Individuals with autism spectrum disorder (ASD) exhibit severe difficulties in
social interaction, motor coordination, behavioral flexibility, and atypical sensory processing …
social interaction, motor coordination, behavioral flexibility, and atypical sensory processing …
A two-hit model of autism: Adolescence as the second hit
Adolescence brings dramatic changes in behavior and neural organization. Unfortunately,
for some 30% of individuals with autism, there is marked decline in adaptive functioning …
for some 30% of individuals with autism, there is marked decline in adaptive functioning …
Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders
JJ Hutsler, H Zhang - Brain research, 2010 - Elsevier
Multiple types of indirect evidence have been used to support theories of altered cortical
connectivity in autism spectrum disorders (ASD). In other developmental disorders reduced …
connectivity in autism spectrum disorders (ASD). In other developmental disorders reduced …