ABC transporters are essential for cellular physiology. Humans have 48 ABC genes
organized into seven distinct families. Of these genes, 44 (in five distinct families) encode for …

The ATP‐binding cassette (ABC) transporter superfamily comprises membrane proteins that
efflux various substrates across extra‐and intracellular membranes. Mutations in ABC genes …

Cardiovascular complications due to accelerated arterial stiffening and atherosclerosis are
the leading cause of morbimortality in Western society. Both pathologies are frequently …

This article explores contemporary biopolitics in the light of Michel Foucault's oft quoted
suggestion that contemporary politics callslife itself'into question. It suggests that recent …

Chemotherapeutics are the most effective treatment for metastatic tumours. However, the
ability of cancer cells to become simultaneously resistant to different drugs—a trait known as …

Adenosine triphosphate (ATP)-binding cassette (ABC) transporters are a 48-member
superfamily of membrane proteins that actively transport a variety of biological substrates …

Effective treatment of metastatic cancers usually requires the use of toxic chemotherapy. In
most cases, multiple drugs are used, as resistance to single agents occurs almost …

The transport of specific molecules across lipid membranes is an essential function of all
living organisms and a large number of specific transporters have evolved to carry out this …

Transporters influence the disposition of chemicals within the body by participating in
absorption, distribution, and elimination. Transporters of the solute carrier family (SLC) …

with the matrix and with the periodicity of negative charges on collagen. Crystals initially
form octacalcium phosphate [Ca8H2 (PO4) 6· 5H2O], which reorganizes and seeds epitaxial …