Screening and testing for endocrine disruption in fish—biomarkers as “signposts,” not “traffic lights,” in risk assessment

TH Hutchinson, GT Ankley, H Segner… - Environmental health …, 2006 - ehp.niehs.nih.gov
Biomarkers are currently best used as mechanistic “signposts” rather than as “traffic lights” in
the environmental risk assessment of endocrine-disrupting chemicals (EDCs). In field …

The effects of estrogenic and androgenic endocrine disruptors on the immune system of fish: a review

S Milla, S Depiereux, P Kestemont - Ecotoxicology, 2011 - Springer
During the last decade, a number of studies have shown that, in addition to their classically
described reproductive function, estrogens and androgens also regulate the immune system …

Copper-induced oxidative stress in three-spined stickleback: relationship with hepatic metal levels

W Sanchez, O Palluel, L Meunier, M Coquery… - Environmental …, 2005 - Elsevier
The aim of this study was to characterise biomarker responses in three-spined sticklebacks
exposed to copper. For this purpose, adult sticklebacks were exposed for 3 weeks to copper …

Molecular biomarkers of endocrine disruption in small model fish

S Scholz, I Mayer - Molecular and Cellular Endocrinology, 2008 - Elsevier
A wide range of environmental contaminants can interfere with hormonal regulation in
vertebrates. These endocrine disrupting chemicals (EDCs) are of high relevance for human …

[图书][B] Biology of the three-spined stickleback

S Ostlund-Nilsson, I Mayer, FA Huntingford - 2006 - taylorfrancis.com
Highlighting the growing importance of the sticklebacks as a model species in emerging
fields such as molecular genetics, genomics, and environmental toxicology, Biology of the …

Biomarkers and integrated environmental risk assessment: are there more questions than answers?

JA Hagger, MB Jones, DRP Leonard… - Integrated …, 2006 - Wiley Online Library
The introduction of the European Commission's Water Framework Directive (WFD;
2000/60/EC) established a new era in environmental risk assessment. In addition to …

Altered reproduction in fish exposed to pulp and paper mill effluents: roles of individual compounds and mill operating conditions

LM Hewitt, TG Kovacs, MG Dubé… - … and Chemistry: An …, 2008 - Wiley Online Library
For the last 20 years, studies conducted in North America, Scandinavia, and New Zealand
have shown that pulp and paper mill effluents affect fish reproduction. Despite the level of …

Surveys of plasma vitellogenin and intersex in male flounder (Platichthys flesus) as measures of endocrine disruption by estrogenic contamination in United Kingdom …

MF Kirby, YT Allen, RA Dyer, SW Feist… - … and Chemistry: An …, 2004 - Wiley Online Library
Plasma vitellogenin (VTG) concentrations and the presence of the ovo‐testis (intersex)
condition have been recorded in male flounder (Platichthys flesus) captured from several …

Heterogeneous genomic differentiation in marine threespine sticklebacks: adaptation along an environmental gradient

J DeFaveri, PR Jonsson, J Merilä - Evolution, 2013 - academic.oup.com
Evolutionary divergence among populations occupying ecologically distinct environments
can occur even in the face of on-going gene flow. However, the genetic underpinnings, as …

Bioassay-derived androgenic and estrogenic activity in municipal sewage in Australia and New Zealand

FDL Leusch, HF Chapman, MR van den Heuvel… - Ecotoxicology and …, 2006 - Elsevier
Raw sewage and sewage at various stages of treatment were sampled from 15 municipal
sewage treatment plants in south Queensland (Australia) and Canterbury (New Zealand) …