Since Flemming described a nuclear substance in the nineteenth century and named it
“chromatin,” this substance has fascinated biologists. What is the structure of chromatin …

Although it was originally believed that enhancers activate only the nearest promoter, recent
global analyses enabled by high-throughput technology suggest that the network of …

The eukaryotic genome is organized within cells as chromatin. For proper information
output, higher-order chromatin structures can be regulated dynamically. How such structures …

Genomic DNA is organized three-dimensionally in the nucleus, and is thought to form
compact chromatin domains. Although chromatin compaction is known to be essential for …

Eukaryotic chromatin is a negatively charged long polymer composed of genomic DNA,
histones, and various proteins. The charged property causes the chromatin structure to be …

The spatio-temporal organization of chromatin in the eukaryotic cell nucleus is of vital
importance for transcription, DNA replication and genome maintenance. Each of these …

Understanding chromatin organization and dynamics is important, since they crucially affect
DNA functions. In this study, we investigate chromatin dynamics by statistically analyzing …

Background The merging of two diverged genomes can result in hybrid offspring that
phenotypically differ greatly from both parents. In plants, interspecific hybridization plays …

The mammalian genome is organized into submegabase-sized chromatin domains (CDs)
including topologically associating domains, which have been identified using chromosome …

In eukaryotic cells, highly condensed inactive/silenced chromatin has long been called
“heterochromatin.” However, recent research suggests that such regions are in fact not fully …