Current and emerging strategies to combat antimalarial resistance
C Rasmussen, P Alonso, P Ringwald - Expert Review of Anti …, 2022 - Taylor & Francis
Introduction Since the spread of chloroquine resistance in Plasmodium falciparum in the
1960s, recommendations have been made on how to respond to antimalarial resistance …
1960s, recommendations have been made on how to respond to antimalarial resistance …
[HTML][HTML] Artemisinin and multidrug-resistant Plasmodium falciparum–a threat for malaria control and elimination
M Dhorda, C Amaratunga… - Current opinion in …, 2021 - journals.lww.com
Enhancing the geographic coverage of surveillance for resistance will be key to ensure
prompt detection of emerging resistance in order to implement effective countermeasures …
prompt detection of emerging resistance in order to implement effective countermeasures …
Plasmodium falciparum resistant to artemisinin and diagnostics have emerged in Ethiopia
AA Fola, SM Feleke, H Mohammed, BG Brhane… - Nature …, 2023 - nature.com
Diagnosis and treatment of Plasmodium falciparum infections are required for effective
malaria control and are pre-requisites for malaria elimination efforts; hence we need to …
malaria control and are pre-requisites for malaria elimination efforts; hence we need to …
[HTML][HTML] Plasmodium falciparum resistance to ACTs: Emergence, mechanisms, and outlook
Emergence and spread of resistance in Plasmodium falciparum to the frontline treatment
artemisinin-based combination therapies (ACTs) in the epicenter of multidrug resistance of …
artemisinin-based combination therapies (ACTs) in the epicenter of multidrug resistance of …
Resistance to artemisinin combination therapies (ACTs): do not forget the partner drug!
C Nsanzabana - Tropical medicine and infectious disease, 2019 - mdpi.com
Artemisinin-based combination therapies (ACTs) have become the mainstay for malaria
treatment in almost all malaria endemic settings. Artemisinin derivatives are highly potent …
treatment in almost all malaria endemic settings. Artemisinin derivatives are highly potent …
Pre-existing partner-drug resistance to artemisinin combination therapies facilitates the emergence and spread of artemisinin resistance: a consensus modelling study
Background Artemisinin-resistant genotypes of Plasmodium falciparum have now emerged
a minimum of six times on three continents despite recommendations that all artemisinins be …
a minimum of six times on three continents despite recommendations that all artemisinins be …
Prevalence of mutations associated with artemisinin partial resistance and sulfadoxine–pyrimethamine resistance in 13 regions in Tanzania in 2021: a cross-sectional …
Background The emergence of the artemisinin partial resistance (ART-R) mutation in the
Plasmodium falciparum kelch13 gene (k13), Arg561His, in Rwanda and the regional …
Plasmodium falciparum kelch13 gene (k13), Arg561His, in Rwanda and the regional …
Genetic diversity and drug resistance surveillance of Plasmodium falciparum for malaria elimination: is there an ideal tool for resource-limited sub-Saharan Africa?
TO Apinjoh, A Ouattara, VPK Titanji, A Djimde… - Malaria journal, 2019 - Springer
The intensification of malaria control interventions has resulted in its global decline, but it
remains a significant public health burden especially in sub-Saharan Africa (sSA) …
remains a significant public health burden especially in sub-Saharan Africa (sSA) …
Effectiveness and safety of intermittent preventive treatment with dihydroartemisinin–piperaquine or artesunate–amodiaquine for reducing malaria and related …
Background In high transmission settings, most school-aged children harbour malaria
parasites without showing symptoms, often leading to anaemia and possibly impaired …
parasites without showing symptoms, often leading to anaemia and possibly impaired …
Persistence of chloroquine resistance alleles in malaria endemic countries: a systematic review of burden and risk factors
Background Chloroquine, a previous highly efficacious, easy to use and affordable anti-
malarial agent was withdrawn from malaria endemic regions due to high levels of …
malarial agent was withdrawn from malaria endemic regions due to high levels of …