Restricting retrotransposons: a review
JL Goodier - Mobile DNA, 2016 - Springer
Retrotransposons have generated about 40% of the human genome. This review examines
the strategies the cell has evolved to coexist with these genomic “parasites”, focussing on …
the strategies the cell has evolved to coexist with these genomic “parasites”, focussing on …
The RNA-binding protein repertoire of embryonic stem cells
RNA-binding proteins (RBPs) have essential roles in RNA-mediated gene regulation, and
yet annotation of RBPs is limited mainly to those with known RNA-binding domains. To …
yet annotation of RBPs is limited mainly to those with known RNA-binding domains. To …
Transposable elements at the center of the crossroads between embryogenesis, embryonic stem cells, reprogramming, and long non-coding RNAs
AP Hutchins, D Pei - Science bulletin, 2015 - Springer
Transposable elements (TEs) are mobile genomic sequences of DNA capable of
autonomous and non-autonomous duplication. TEs have been highly successful, and nearly …
autonomous and non-autonomous duplication. TEs have been highly successful, and nearly …
Dissolution of ribonucleoprotein condensates by the embryonic stem cell protein L1TD1
SW Jin, Y Seong, D Yoon, YS Kwon… - Nucleic acids …, 2024 - academic.oup.com
L1TD1 is a cytoplasmic RNA-binding protein specifically expressed in pluripotent stem cells
and, unlike its mouse ortholog, is essential for the maintenance of stemness in human cells …
and, unlike its mouse ortholog, is essential for the maintenance of stemness in human cells …
RNA‐Binding Protein L1TD1 Interacts with LIN28 via RNA and is Required for Human Embryonic Stem Cell Self‐Renewal and Cancer Cell Proliferation
Human embryonic stem cells (hESC) have a unique capacity to self‐renew and differentiate
into all the cell types found in human body. Although the transcriptional regulators of …
into all the cell types found in human body. Although the transcriptional regulators of …
Post-transcriptional regulation of the pluripotent state
Q Chen, G Hu - Current opinion in genetics & development, 2017 - Elsevier
Pluripotency describes the developmental capacity to give rise to all cell types in the adult
body. A comprehensive understanding of the molecular mechanisms that regulate …
body. A comprehensive understanding of the molecular mechanisms that regulate …
Prostaglandin D2 acts through the Dp2 receptor to influence male germ cell differentiation in the foetal mouse testis
B Moniot, S Ujjan, J Champagne, H Hirai… - …, 2014 - journals.biologists.com
Through intercellular signalling, the somatic compartment of the foetal testis is able to
program primordial germ cells to undergo spermatogenesis. Fibroblast growth factor 9 and …
program primordial germ cells to undergo spermatogenesis. Fibroblast growth factor 9 and …
RNA-binding proteins in pluripotency, differentiation, and reprogramming
Embryonic stem cell maintenance, differentiation, and somatic cell reprogramming require
the interplay of multiple pluripotency factors, epigenetic remodelers, and extracellular …
the interplay of multiple pluripotency factors, epigenetic remodelers, and extracellular …
Essential roles of ECAT15-2/Dppa2 in functional lung development
T Nakamura, M Nakagawa, T Ichisaka… - … and cellular biology, 2011 - Taylor & Francis
Many transcription factors and DNA binding proteins play essential roles in the development
of organs in which they are highly and/or specifically expressed. Embryonic stem cell (ESC) …
of organs in which they are highly and/or specifically expressed. Embryonic stem cell (ESC) …
The L1TD1 protein interactome reveals the importance of post-transcriptional regulation in human pluripotency
The RNA-binding protein L1TD1 is one of the most specific and abundant proteins in
pluripotent stem cells and is essential for the maintenance of pluripotency in human cells …
pluripotent stem cells and is essential for the maintenance of pluripotency in human cells …