Advances in development and application of influenza vaccines

J Chen, J Wang, J Zhang, H Ly - Frontiers in immunology, 2021 - frontiersin.org
Influenza A virus is one of the most important zoonotic pathogens that can cause severe
symptoms and has the potential to cause high number of deaths and great economic loss …

Potential cross-species transmission of highly pathogenic avian influenza H5 subtype (HPAI H5) viruses to humans calls for the development of H5-specific and …

P Huang, L Sun, J Li, Q Wu, N Rezaei, S Jiang, C Pan - Cell discovery, 2023 - nature.com
In recent years, highly pathogenic avian influenza H5 subtype (HPAI H5) viruses have been
prevalent around the world in both avian and mammalian species, causing serious …

Progress towards the development of a universal influenza vaccine

WC Wang, EE Sayedahmed, S Sambhara, SK Mittal - Viruses, 2022 - mdpi.com
Influenza viruses are responsible for millions of cases globally and significantly threaten
public health. Since pandemic and zoonotic influenza viruses have emerged in the last 20 …

Adenoviral vector-based vaccine platforms for developing the next generation of influenza vaccines

EE Sayedahmed, A Elkashif, M Alhashimi, S Sambhara… - Vaccines, 2020 - mdpi.com
Ever since the discovery of vaccines, many deadly diseases have been contained
worldwide, ultimately culminating in the eradication of smallpox and polio, which …

Adenoviral vectors as vaccines for emerging avian influenza viruses

LJ Kerstetter, S Buckley, CM Bliss… - Frontiers in …, 2021 - frontiersin.org
It is evident that the emergence of infectious diseases, which have the potential for spillover
from animal reservoirs, pose an ongoing threat to global health. Zoonotic transmission …

Progress in the development of universal influenza vaccines

W Sun, T Luo, W Liu, J Li - Viruses, 2020 - mdpi.com
Influenza viruses pose a significant threat to human health. They are responsible for a large
number of deaths annually and have a serious impact on the global economy. There are …

Adenoviral vector‐based platforms for developing effective vaccines to combat respiratory viral infections

A Elkashif, M Alhashimi… - Clinical & …, 2021 - Wiley Online Library
Since the development of the first vaccine against smallpox over two centuries ago,
vaccination strategies have been at the forefront of significantly impacting the incidences of …

Current use of adenovirus vectors and their production methods

EE Sayedahmed, R Kumari, SK Mittal - Viral Vectors for Gene Therapy …, 2019 - Springer
Various adenovirus (AdV) vector systems have proven to be lucrative options for gene
delivery. They can serve as potential vaccine candidates for prevention of several common …

Construction and evaluation of the immunogenicity and protective efficacy of recombinant replication-deficient human Adenovirus-5 expressing genotype VII …

T Xu, T Xiong, W Xie, J Wu, X Liu, G Li, Y Lv, L Li… - Vaccines, 2023 - mdpi.com
Newcastle disease (ND) and infectious bursal disease (IBD) are two key infectious diseases
that significantly threaten the health of the poultry industry. Although existing vaccinations …

An inactivated influenza virus vaccine approach to targeting the conserved hemagglutinin stalk and M2e domains

W Sun, A Zheng, R Miller, F Krammer, P Palese - Vaccines, 2019 - mdpi.com
Universal influenza virus vaccine candidates that focus on the conserved hemagglutinin
(HA) stalk domain and the extracellular domain of the matrix protein 2 (M2e) have been …