Mitochondria are key determinants of cellular health. However, the functional role of
mitochondria varies from cell to cell depending on the relative demands for energy …

Within living cells, mitochondria are considered relevant sources of reactive oxygen species
(ROS) and are exposed to reactive nitrogen species (RNS). During the last decade …

It is increasingly acknowledged that a sex and gender specificity affects the occurrence,
development, and consequence of a plethora of pathologies. Mitochondria are considered …

ABSTRACT Calcium (Ca2+) is a key player in the regulation of many cell functions. Just like
Ca2+, mitochondria are ubiquitous, versatile, and dynamic players in determining both cell …

The mitochondrial inner membrane can reshape under different physiological conditions.
How, at which frequency this occurs in living cells, and the molecular players involved are …

Mitochondria are essential organelles performing important cellular functions ranging from
bioenergetics and metabolism to apoptotic signaling and immune responses. They are …

Brain computation is metabolically expensive and requires the supply of significant amounts
of energy. Mitochondria are highly specialized organelles whose main function is to …

Purified mitochondrial ATP synthase has been shown to form Ca2+-activated, large
conductance channel activity similar to that of mitochondrial megachannel (MMC) or …

Mitochondrial functions are intrinsically linked to their morphology and membrane
ultrastructure. Characterizing abnormal mitochondrial structural features may thus provide …

Since the discovery of the existence of superassemblies between mitochondrial respiratory
complexes, such superassemblies have been the object of a passionate debate. It is …