Severe injuries or diseases affecting the peripheral and central nervous systems can result
in impaired organ function and permanent paralysis. Conventional interventions, such as …

Over the last decade, adipose‐derived stem cells (ADSCs) have attracted increasing
attention in the field of regenerative medicine. ADSCs appear to be the most advantageous …

Postoperative abdominal adhesions are a common problem after surgery and can produce
serious complications. Current antiadhesive strategies focus mostly on physical barriers and …

Extensive macrophage inflammatory responses and osteoclast formation are predominant
during inflammatory or infective osteolysis. Mesenchymal stem cell (MSC)-derived small …

Peripheral nerve injury (PNI) remains a severe clinical problem with debilitating
consequences. Mesenchymal stem cell (MSC)-based therapy is promising, but the problems …

Abstract Background Schwann cells (SCs) respond to nerve injury by transforming into the
repair-related cell phenotype, which can provide the essential signals and spatial cues to …

Biomaterials can modulate the local immune and repair-supportive microenvironments to
promote peripheral nerve regeneration. Inorganic bioceramics have been widely used for …

Repairing critical bone defects is a complex problem in the clinic. The periosteum rich in
nerve plays a vital role in initiating and regulating bone regeneration. However, current …

Patients with peripheral nerve injuries would highly likely suffer from chronic neuropathic
pain even after surgical intervention. The primary reasons for this involve sustained …

The use of autografted nerve in surgical repair of peripheral nerve injuries (PNI) is severely
limited due to donor site morbidity and restricted tissue availability. As an alternative …