Sex hormones have been implicated in neurite outgrowth, synaptogenesis, dendritic
branching, myelination and other important mechanisms of neural plasticity. Here we review …

Population aging is one of the most significant social changes of the twenty-first century. This
increase in longevity is associated with a higher prevalence of chronic diseases, further …

Synucleinopathies are a group of neurodegenerative disorders caused by the accumulation
of toxic species of α-synuclein. The common clinical features are chronic progressive …

Monoamine oxidase types A and B (MAO-A, MAO-B) regulate the levels of monoamine
neurotransmitters in the brain, and their dysfunction may be involved in the pathogenesis …

There has been a substantial research effort to design multi-target ligands for the treatment
of Alzheimer's disease (AD), an approach that is moved by the knowledge that AD is a …

The oxygenation of polyunsaturated fatty acids such as arachidonic and linoleic acid
through enzymes like lipoxygenases (LOXs) are common and often leads to the production …

Prostate cancer (PCa) is a major cause of mortality and morbidity in men. Available
therapies yield limited outcome. We explored anti-PCa activity in a polyphenol-rich fraction …

Monoamine oxidases (MAOs) are flavoproteins of the outer mitochondrial membrane that
catalyze the oxidative deamination of biogenic and xenobiotic amines. In mammals there …

This study depicted the effect of IL-13 and 13 (S) HpODE (the endogenous product during IL-
13 activation) in the process of cancer cell apoptosis. We examined the role of both IL-13 …

Inadequate treatment response occurs in approximately 40% of major depressive episodes
(MDEs), and one approach to solve this is careful matching of treatment to the specific …