Ovarian cancer is a leading cause of death among women with gynecological cancers, and
is often diagnosed at advanced stages, leading to poor outcomes. This review explores …

The RAS family of proteins is among the most frequently mutated genes in human
malignancies. In ovarian cancer (OC), the most lethal gynecological malignancy, RAS …

Cancer stem cells (CSCs) may contribute to an increased risk of recurrence in ovarian
cancer (OC). Further research is needed to identify associations between CSC markers and …

Ovarian cancer, a deadly female reproductive system disease, is a significant challenge in
medical research due to its notorious lethality. Addressing ovarian cancer in the current …

Ovarian cancer stem-like cells (CSCs) have been implicated in tumor recurrence,
metastasis, and drug resistance. Accumulating evidence has demonstrated the antitumor …

Simple Summary High-grade serous ovarian carcinoma (HGSOC) has poor prognosis for
patients due to its high rate of recurrence and acquired resistance to therapy. MEK1/2 …

Ovarian cancer, especially high-grade serous type, is the most lethal gynecological
malignancy. The lack of screening programs and the scarcity of symptomatology result in the …

Background Cancer stem cells (CSCs) have emerged as pivotal players in tumorigenesis,
disease progression, and resistance to therapies. Objective This comprehensive review …

Over the past decades, cancer stem cells (CSCs) have emerged as a critical subset of tumor
cells associated with tumor recurrence and resistance to chemotherapy. Understanding the …

Simple Summary Survival outcomes with standard cytotoxic chemotherapy are poor, and
most patients with ovarian cancer will die with platinum-resistant disease. This may reflect …