With all the advances in tissue engineering for construction of fully functional skin tissue,
complete regeneration of chronic wounds is still challenging. Since immune reaction to the …

As the most dominant cell type in the skin, keratinocytes play critical roles in wound repair
not only as structural cells but also exerting important immune functions. This review focuses …

Macrophages are key immune cells that respond to infections, and modulate
pathophysiological conditions such as wound healing. By possessing phagocytic activities …

Extracellular vesicles (EVs) are nanoscale membrane vesicles released by donor cells that
can be taken up by recipient cells. The study of EVs has the potential to identify unknown …

Developing multifunctional wound dressings capable of inducing rapid angiogenesis
provides promise for diabetic wound healing, and triggering proper immune responses has …

In the past decade, there has been a shift in research, clinical development, and commercial
activity to exploit the many physiological roles of RNA for use in medicine. With the rapid …

Complexity and difficulties in wound management are pressing concerns that affect patients'
quality of life and may result in tissue infection, necrosis, and loss of local and systemic …

Background The past few years have witnessed a significant increase in research related to
plant-derived extracellular vesicles (PDEVs) in biological and medical applications. Using …

Each year, millions of individuals suffer from a non-healing wound, abnormal scarring, or
injuries accompanied by an infection. For these cases, scientists are searching for new …

Chronic wounds affect healthcare systems and increase the risk of infection. Despite the
clinical demand for improving healing, an effective and safe therapeutic approach is still …