Biomaterials for bone regenerative engineering

X Yu, X Tang, SV Gohil… - Advanced healthcare …, 2015 - Wiley Online Library
Strategies for bone tissue regeneration have been continuously evolving for the last 25
years since the introduction of the “tissue engineering” concept. The convergence of the life …

Thiol–norbornene photoclick hydrogels for tissue engineering applications

CC Lin, CS Ki, H Shih - Journal of applied polymer science, 2015 - Wiley Online Library
ABSTRACT Thiol–norbornene (thiol–ene) photoclick hydrogels have emerged as a diverse
material system for tissue engineering applications. These hydrogels are crosslinked …

[PDF][PDF] Recent applications of polyethylene glycols (PEGs) and PEG derivatives

D Hutanu, MD Frishberg, L Guo, CC Darie - Mod. Chem. Appl, 2014 - jenkemusa.com
Numerous applications of polyethylene glycol derived polymers (PEGs) have been reported
in the scientific literature for many years. With increasing experience and comfort by …

Versatile synthetic alternatives to Matrigel for vascular toxicity screening and stem cell expansion

EH Nguyen, WT Daly, NNT Le, M Farnoodian… - Nature biomedical …, 2017 - nature.com
The physiological relevance of Matrigel as a cell-culture substrate and in angiogenesis
assays is often called into question. Here, we describe an array-based method for the …

High-throughput routes to biomaterials discovery

F Soheilmoghaddam, M Rumble… - Chemical …, 2021 - ACS Publications
Many existing clinical treatments are limited in their ability to completely restore decreased
or lost tissue and organ function, an unenviable situation only further exacerbated by a …

Human vascular tissue models formed from human induced pluripotent stem cell derived endothelial cells

DG Belair, JA Whisler, J Valdez, J Velazquez… - Stem cell reviews and …, 2015 - Springer
Here we describe a strategy to model blood vessel development using a well-defined
induced pluripotent stem cell-derived endothelial cell type (iPSC-EC) cultured within …

A combination of matrix stiffness and degradability dictate microvascular network assembly and remodeling in cell-laden poly (ethylene glycol) hydrogels

NE Friend, AJ McCoy, JP Stegemann, AJ Putnam - Biomaterials, 2023 - Elsevier
The formation of functional capillary blood vessels that can sustain the metabolic demands
of transplanted parenchymal cells remains one of the biggest challenges to the clinical …

Comparison between polypyridyl and cyclometalated ruthenium (II) complexes: anticancer activities against 2D and 3D cancer models

H Huang, P Zhang, H Chen, L Ji… - Chemistry–A European …, 2015 - Wiley Online Library
The aim of this study was to illustrate the dramatically different anticancer activities between
coordinatively saturated polypyridyl (1 a–4 a) and cyclometalated (1 b–4 b) ruthenium (II) …

Stable engineered vascular networks from human induced pluripotent stem cell-derived endothelial cells cultured in synthetic hydrogels

MR Zanotelli, H Ardalani, J Zhang, Z Hou, EH Nguyen… - Acta biomaterialia, 2016 - Elsevier
Here, we describe an in vitro strategy to model vascular morphogenesis where human
induced pluripotent stem cell-derived endothelial cells (iPSC-ECs) are encapsulated in …

A peptide functionalized poly (ethylene glycol)(PEG) hydrogel for investigating the influence of biochemical and biophysical matrix properties on tumor cell migration

SP Singh, MP Schwartz, JY Lee, BD Fairbanks… - Biomaterials …, 2014 - pubs.rsc.org
To address the challenges associated with defined control over matrix properties in 3D cell
culture systems, we employed a peptide functionalized poly (ethylene glycol)(PEG) hydrogel …