[HTML][HTML] Mechanotransduction in tumor dynamics modeling
Mechanotherapy is a groundbreaking approach to impact carcinogenesis. Cells sense and
respond to mechanical stimuli, translating them into biochemical signals in a process known …
respond to mechanical stimuli, translating them into biochemical signals in a process known …
Biomechanical modelling of tumor growth with chemotherapeutic treatment: a review
The efficiency of chemotherapy in the treatment of cancer depends on the administration
schedule, such as dosage, timing and frequency, and the release control if self-assembled …
schedule, such as dosage, timing and frequency, and the release control if self-assembled …
Quantifying solid stress and elastic energy from excised or in situ tumors
Solid stress, distinct from both tissue stiffness and fluid pressure, is a mechanical stress that
is often elevated in both murine and human tumors. The importance of solid stress in tumor …
is often elevated in both murine and human tumors. The importance of solid stress in tumor …
Strain stiffening retards growth instability in residually stressed biological tissues
Soft biological tissues often exhibit notable strain stiffening under increasing stretch, and this
can have significant effects on tissue growth and morphological development, such as …
can have significant effects on tissue growth and morphological development, such as …
Dynamic plastic deformation and failure mechanisms of individual microcapsule and its polymeric composites
Functional materials are widely used by introducing functional microcapsules in the matrix.
The individual microcapsule can be regarded as core-shell structure in micro-level. In this …
The individual microcapsule can be regarded as core-shell structure in micro-level. In this …
A mechanistically motivated constitutive model of biopolymer hydrogels with structural evolution
Q Meng, X Shi - Journal of the Mechanics and Physics of Solids, 2023 - Elsevier
Understanding the deformation behavior of biopolymer hydrogels would aid in the design of
artificial hydrogels and nanoparticle-based drug delivery systems, which have been …
artificial hydrogels and nanoparticle-based drug delivery systems, which have been …
Cells competition in tumor growth poroelasticity
M Fraldi, AR Carotenuto - Journal of the Mechanics and Physics of Solids, 2018 - Elsevier
Growth of biological tissues has been recently treated within the framework of Continuum
Mechanics, by adopting heterogeneous poroelastic models where the interaction between …
Mechanics, by adopting heterogeneous poroelastic models where the interaction between …
Mechanical behavior of multi-cellular spheroids under osmotic compression
The internal and external mechanical environment plays an important role in tumorogenesis.
As a proxy of an avascular early state tumor, we use multicellular spheroids, a composite …
As a proxy of an avascular early state tumor, we use multicellular spheroids, a composite …
Interfacial organization and forces arising from epithelial–cancerous monolayer interactions
The interfacial interactions between epithelia and cancer cells have profound relevance for
tumor development and metastasis. Through monolayer confrontation of MCF10A …
tumor development and metastasis. Through monolayer confrontation of MCF10A …
A large deformation theory for coupled swelling and growth with application to growing tumors and bacterial biofilms
S Chockalingam, T Cohen - Journal of the Mechanics and Physics of Solids, 2024 - Elsevier
There is significant interest in modeling the mechanics and physics of growth of soft
biological systems such as tumors and bacterial biofilms. Solid tumors account for more than …
biological systems such as tumors and bacterial biofilms. Solid tumors account for more than …