Mechanotherapy is a groundbreaking approach to impact carcinogenesis. Cells sense and
respond to mechanical stimuli, translating them into biochemical signals in a process known …

The efficiency of chemotherapy in the treatment of cancer depends on the administration
schedule, such as dosage, timing and frequency, and the release control if self-assembled …

Solid stress, distinct from both tissue stiffness and fluid pressure, is a mechanical stress that
is often elevated in both murine and human tumors. The importance of solid stress in tumor …

Soft biological tissues often exhibit notable strain stiffening under increasing stretch, and this
can have significant effects on tissue growth and morphological development, such as …

Functional materials are widely used by introducing functional microcapsules in the matrix.
The individual microcapsule can be regarded as core-shell structure in micro-level. In this …

Understanding the deformation behavior of biopolymer hydrogels would aid in the design of
artificial hydrogels and nanoparticle-based drug delivery systems, which have been …

Growth of biological tissues has been recently treated within the framework of Continuum
Mechanics, by adopting heterogeneous poroelastic models where the interaction between …

The internal and external mechanical environment plays an important role in tumorogenesis.
As a proxy of an avascular early state tumor, we use multicellular spheroids, a composite …

The interfacial interactions between epithelia and cancer cells have profound relevance for
tumor development and metastasis. Through monolayer confrontation of MCF10A …

There is significant interest in modeling the mechanics and physics of growth of soft
biological systems such as tumors and bacterial biofilms. Solid tumors account for more than …