Two component regulatory systems and antibiotic resistance in Gram-negative pathogens

AY Bhagirath, Y Li, R Patidar, K Yerex, X Ma… - International journal of …, 2019 - mdpi.com
Gram-negative pathogens such as Klebsiella pneumoniae, Acinetobacter baumannii, and
Pseudomonas aeruginosa are the leading cause of nosocomial infections throughout the …

An overview of viral mutagenesis and the impact on pathogenesis of SARS-CoV-2 variants

MZI Khan, A Nazli, H Al-Furas, MI Asad, I Ajmal… - Frontiers in …, 2022 - frontiersin.org
Viruses are submicroscopic, obligate intracellular parasites that carry either DNA or RNA as
their genome, protected by a capsid. Viruses are genetic entities that propagate by using the …

Diagnostic accuracy and prognostic value of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios in septic patients outside the intensive care unit

S Spoto, DM Lupoi, E Valeriani, M Fogolari… - Medicina, 2021 - mdpi.com
Background and Objectives: The aim of this study was to evaluate the diagnostic accuracy
and prognostic value of neutrophil-to-lymphocyte (NLR) and platelet-to-lymphocyte (PLR) …

Transmission of Carbapenem-Resistant Klebsiella pneumoniae in US Hospitals

CL Luterbach, L Chen, L Komarow… - Clinical Infectious …, 2023 - academic.oup.com
Abstract Background Carbapenem-resistant Klebsiella pneumoniae (CR Kp) is the most
prevalent carbapenem-resistant Enterobacterales in the United States. We evaluated CR Kp …

Spatiotemporal dynamics of multidrug resistant bacteria on intensive care unit surfaces

AW D'Souza, RF Potter, M Wallace, A Shupe… - Nature …, 2019 - nature.com
Bacterial pathogens that infect patients also contaminate hospital surfaces. These
contaminants impact hospital infection control and epidemiology, prompting quantitative …

Incidence of drug-resistant hospital-associated Gram-negative bacterial infections, the accompanying risk factors, and clinical outcomes with treatment

L Badger-Emeka, AS Al Rashed, RY Aljindan… - Antibiotics, 2023 - mdpi.com
Extensive drug resistance to bacterial infections in hospitalised patients is accompanied by
high morbidity and mortality rates due to limited treatment options. This study investigated …

Multi-drug resistant Pseudomonas aeruginosa nosocomial strains: Molecular epidemiology and evolution

S Angeletti, E Cella, M Prosperi, S Spoto… - Microbial …, 2018 - Elsevier
Pseudomonas aeruginosa causes a wide variety of nosocomial infections. In the study,
phylogenetic, selective pressure analysis and homology modelling were applied to oprD …

MALDI-TOF MS Identification and Clustering Applied to Enterobacter Species in Nosocomial Setting

L De Florio, E Riva, A Giona, E Dedej… - Frontiers in …, 2018 - frontiersin.org
Enterobacter microorganisms cause important bacterial infections in humans. Recently,
carbapenem resistant isolates carrying the bla KPC gene were described and their clonal …

Melatonin-enhanced biosynthesis of antimicrobial AgNPs by improving the phytochemical reducing potential of a callus culture of Ocimum basilicum L. var. thyrsiflora

T Khan, BH Abbasi, MS Afridi, F Tanveer, I Ullah… - RSC …, 2017 - pubs.rsc.org
Herein, we describe the green synthesis of silver nanoparticles (AgNPs) using Ocimum
basilicum L. var. thyrsiflora leaf derived callus extracts formed in response to 9.0 μM of …

Active surveillance cultures and Procalcitonin in combination with clinical data to guide empirical antimicrobial therapy in hospitalized medical patients with Sepsis

S Spoto, J Daniel Markley, E Valeriani… - Frontiers in …, 2022 - frontiersin.org
Objective The prevalence of colonization with multidrug-resistant organisms (MDRO) has
increased over the last decade, reaching levels as high as 23% in certain patient …