Premature obesity-related mortality is caused by cardiovascular and pulmonary diseases,
type 2 diabetes mellitus, physical disabilities, osteoarthritis, and certain types of cancer …

Gustation or the sense of taste is a primary sense, which functions as a gatekeeper for
substances that enter the body. Animals, including humans, ingest foods that contain …

Embryonic taste bud primordia are specified as taste placodes on the tongue surface and
differentiate into the first taste receptor cells (TRCs) at birth. Throughout adult life, TRCs are …

Mutations in SHH and several other genes encoding components of the Hedgehog
signaling pathway have been associated with holoprosencephaly syndromes, with …

Development of mammalian auditory epithelium, the organ of Corti, requires precise control
of both cell cycle withdrawal and differentiation. Sensory progenitors (prosensory cells) in …

Taste buds are the sensory end organs for gustation, mediating sensations of salty, sour,
bitter, sweet and umami as well as other possible modalities, for example, fat and kokumi …

Cancers of the urinary tract, as well as those of the female and male reproductive systems,
account for a large percentage of malignancies worldwide. Mortality is frequently affected by …

Vertebrate skin appendages are incredibly diverse. This diversity, which includes structures
such as scales, feathers, and hair, likely evolved from a shared anatomical placode …

Introduction We have recently demonstrated that Sox10-expressing (Sox10+) cells give rise
to mainly type-III neuronal taste bud cells that are responsible for sour and salt taste. The two …

Sensory receptors across the entire tongue are engaged during eating. However, the tongue
has distinctive regions with taste (fungiform and circumvallate) and non-taste (filiform) …